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10.1186/s43162-021-00047-y http://scihub22266oqcxt.onion/10.1186/s43162-021-00047-y 34121836!8184260!34121836     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=34121836&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Egypt+J+Intern+Med 2021 ; 33 (1): 18 Nephropedia Template TP {{tp|p=34121836|t=2021. Frequency and risk factors for hydroxychloroquine retinopathy among patients with systemic lupus erythematosus |pdf=|usr=}}{{34121836}} gab.com Text Frequency and risk factors for hydroxychloroquine retinopathy among patients with systemic lupus erythematosus JO: Egypt J Intern Med http://www.kidney.de/pget.php?&tw=1&pmid=34121836 #FOAvip BACKGROUND: Hydroxychloroquine (HCQ) is an antimalarial drug, recently used in COVID-19 treatment. Also it is considered over many years the cornerstone in treating systemic lupus erythematosus (SLE) in adults and children. The incidence of retinal affection and retinal toxicity from hydroxychloroquine is rare, but even after the HCQ is stopped, loss of vision may not be reversible and may continue to progress. Fundus autofluorescence (FAF) is one of the screening methods recommended by AAO used for the diagnosis of hydroxychloroquine retinopathy. Our aim is to detect early HCQ-induced retinopathy among SLE patients and the risk factors for its development by using fundus autofluorescence. RESULTS: In the present study, 11.3% of the studied patients had significant visual field changes upon testing. Of those, 6.3% had abnormal fundus autofluorescence. We found a significant statistical relation between hydroxychloroquine retinopathy and the duration and cumulative dose of hydroxychloroquine therapy (p value = 0.003) and decreased best-corrected visual acuity of both eyes (p value = 0.000). There was no relationship between HCQ retinopathy detected by fundus autofluorescence and daily dose of HCQ/kg, age, sex, and SLEDAI score. CONCLUSION: Frequency of SLE patients who had confirmed HCQ-induced retinopathy was 6.3%. Hydroxychloroquine could be safely used in all SLE patients regardless of age, sex, and SLE activity. Routine ophthalmological assessment is recommended for SLE patients who received HCQ especially for those who received HCQ longer than 7 years. Fundus autofluorescence is a modern objective tool which is specific for the early detection of HCQ retinopathy. Twit Text FOAVip Frequency and risk factors for hydroxychloroquine retinopathy among patients with systemic lupus erythematosus ????Egypt J Intern Med http://www.kidney.de/pget.php?&tw=1&pmid=34121836 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34121836 #FOAvip English Wikipedia <ref>{{Cite pmid|34121836}}</ref> Frequency and risk factors for hydroxychloroquine retinopathy among patients with systemic lupus erythematosus #MMPMID34121836 Abdelbaky MSE; El Mamoun TA; Mabrouk FI; Hassan RM Egypt J Intern Med 2021[]; 33 (1): 18 PMID34121836show ga BACKGROUND: Hydroxychloroquine (HCQ) is an antimalarial drug, recently used in COVID-19 treatment. Also it is considered over many years the cornerstone in treating systemic lupus erythematosus (SLE) in adults and children. The incidence of retinal affection and retinal toxicity from hydroxychloroquine is rare, but even after the HCQ is stopped, loss of vision may not be reversible and may continue to progress. Fundus autofluorescence (FAF) is one of the screening methods recommended by AAO used for the diagnosis of hydroxychloroquine retinopathy. Our aim is to detect early HCQ-induced retinopathy among SLE patients and the risk factors for its development by using fundus autofluorescence. RESULTS: In the present study, 11.3% of the studied patients had significant visual field changes upon testing. Of those, 6.3% had abnormal fundus autofluorescence. We found a significant statistical relation between hydroxychloroquine retinopathy and the duration and cumulative dose of hydroxychloroquine therapy (p value = 0.003) and decreased best-corrected visual acuity of both eyes (p value = 0.000). There was no relationship between HCQ retinopathy detected by fundus autofluorescence and daily dose of HCQ/kg, age, sex, and SLEDAI score. CONCLUSION: Frequency of SLE patients who had confirmed HCQ-induced retinopathy was 6.3%. Hydroxychloroquine could be safely used in all SLE patients regardless of age, sex, and SLE activity. Routine ophthalmological assessment is recommended for SLE patients who received HCQ especially for those who received HCQ longer than 7 years. Fundus autofluorescence is a modern objective tool which is specific for the early detection of HCQ retinopathy. ?Frequency and risk factors for hydroxychloroquine retinopathy among pa(epmc).pdf DeepDyve Pubget Overpricing