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10.4081/monaldi.2021.1867

http://scihub22266oqcxt.onion/10.4081/monaldi.2021.1867
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34121379!ä!34121379

suck abstract from ncbi


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pmid34121379      Monaldi+Arch+Chest+Dis 2021 ; 91 (4): ä
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  • Hyperimmune plasma infusion in an immunocompromised Covid-19 patient previously treated for follicular lymphoma #MMPMID34121379
  • Levi G; Rocchetti C; Magri R; Uccelli S; Bottone D; Quadri F; Novali M; Santin AD; Bezzi M
  • Monaldi Arch Chest Dis 2021[Jun]; 91 (4): ä PMID34121379show ga
  • Covid-19 in immunocompromised patients shows a prolonged course and may lead to a poor prognosis. Although data on hyperimmune plasma for treatment of Covid-19 suggest an improved outcome in immunocompetent patients, limited data are currently available in immunocompromised patients. We present the case of a 62-year-old Caucasian woman, who was previously treated with obinutuzumab and bendamustine for follicular lymphoma and showed a prolonged positive test for Covid-19. Since no improvement was observed with standard of care (including remdesivir), the possibility of hyperimmune plasma infusion was discussed. A first dose of hyperimmune plasma was administered, with subsequent onset of fever, increasing inflammatory indexes and worsening radiological findings. Three days later a second dose of plasma was administered. Within twelve hours cough and fever disappeared, and oxygen at rest was discontinued. The patient was discharged 5 days later, and nasopharyngeal swabs resulted negative 16 days after discharge.
  • |*COVID-19[MESH]
  • |*Lymphoma, Follicular/drug therapy[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Immunocompromised Host[MESH]
  • |Middle Aged[MESH]
  • |SARS-CoV-2[MESH]


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