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10.1016/j.jmb.2021.167093

http://scihub22266oqcxt.onion/10.1016/j.jmb.2021.167093
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34116123!8186955!34116123
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suck abstract from ncbi

pmid34116123      J+Mol+Biol 2021 ; 433 (20): 167093
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  • Can We AlphaFold Our Way Out of the Next Pandemic? #MMPMID34116123
  • Higgins MK
  • J Mol Biol 2021[Oct]; 433 (20): 167093 PMID34116123show ga
  • The announcement of the outstanding performance of AlphaFold 2 in the CASP 14 protein structure prediction competition came at the end of a long year defined by the COVID-19 pandemic. With an infectious organism dominating the world stage, the developers of Alphafold 2 were keen to play their part, accurately predicting novel structures of two proteins from SARS-CoV-2. In their blog post of December 2020, they highlighted this contribution, writing "we've also seen signs that protein structure prediction could be useful in future pandemic response efforts". So, what role does structural biology play in guiding vaccine immunogen design and what might be the contribution of AlphaFold 2?
  • |*Software[MESH]
  • |Antibodies, Neutralizing/immunology[MESH]
  • |Drug Design[MESH]
  • |Epitopes/chemistry[MESH]
  • |Humans[MESH]
  • |Membrane Proteins/chemistry/immunology[MESH]
  • |Pandemics/*prevention & control[MESH]
  • |Protein Conformation[MESH]


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