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suck abstract from ncbi


10.1007/s40121-021-00477-9

http://scihub22266oqcxt.onion/10.1007/s40121-021-00477-9
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suck abstract from ncbi

pmid34115314      Infect+Dis+Ther 2021 ; 10 (3): 1407-1418
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  • Impact of Inflammatory Response Modifiers on the Incidence of Hospital-Acquired Infections in Patients with COVID-19 #MMPMID34115314
  • Meira F; Moreno-Garcia E; Linares L; Macaya I; Tome A; Hernandez-Meneses M; Albiach L; Morata L; Letona L; Bodro M; Cozar-Llisto A; Cardozo C; Chumbita M; Pitart C; Ambrosioni J; Rico V; Aguero D; Puerta-Alcalde P; Garcia-Pouton N; Marco F; Garcia-Vidal C; Soriano A; Martinez JA
  • Infect Dis Ther 2021[Sep]; 10 (3): 1407-1418 PMID34115314show ga
  • INTRODUCTION: The study aim was to assess the influence of inflammatory response modifiers, including anti-interleukin-6 (IL-6) biologics and corticosteroids, on the incidence of hospital-acquired infections in patients with coronavirus disease 2019 (COVID-19). METHODS: Case-control study performed at a university hospital from February 26 to May 26, 2020. Cases were defined as patients with COVID-19 who developed hospital-acquired infections. For each case, two controls were selected among patients without infections. Cases and controls were matched obeying three criteria in a hierarchical sequence: length of hospital stay up until the first infection; comorbidity; and need for Intensive care unit (ICU) admission. Conditional logistic regression analysis was used to estimate the association of exposures with being a case. RESULTS: A total of 71 cases and 142 controls were included. Independent predictors for acquiring a hospital infection were chronic liver disease [odds ratio (OR) 16.56, 95% CI 1.87-146.5, p = 0.012], morbid obesity (OR 6.11, 95% CI 1.06-35.4, p = 0.043), current or past smoking (OR 4.15, 95% CI 1.45-11.88, p = 0.008), exposure to hydroxychloroquine (OR 0.2, 95% CI 0.041-1, p = 0.053), and invasive mechanical ventilation (OR 61.5, 95% CI 11.08-341, p
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