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10.1136/bmjopen-2021-049876

http://scihub22266oqcxt.onion/10.1136/bmjopen-2021-049876
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suck abstract from ncbi


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pmid34112645      BMJ+Open 2021 ; 11 (6): e049876
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  • SARS-CoV-2 seroprevalence in students and teachers: a longitudinal study from May to October 2020 in German secondary schools #MMPMID34112645
  • Kirsten C; Unrath M; Luck C; Dalpke AH; Berner R; Armann J
  • BMJ Open 2021[Jun]; 11 (6): e049876 PMID34112645show ga
  • OBJECTIVE: To quantify the number of SARS-CoV-2 infections in secondary schools after their reopening in May 2020. DESIGN: Repeated SARS-CoV-2 seroprevalence study after the reopening of schools and 4 months later. SETTING: Secondary school in Dresden, Germany. PARTICIPANTS: 1538 students grades 8-12 and 507 teachers from 13 schools. INTERVENTIONS: Serial blood sampling and SARS-CoV-2 IgG antibody assessment. PRIMARY AND SECONDARY OUTCOME MEASURE: Seroprevalence of SARS-CoV-2 antibodies in study population. Number of undetected cases. RESULTS: 1538 students and 507 teachers were initially enrolled, and 1334 students and 445 teachers completed both study visits. The seroprevalence for SARS-CoV-2 antibodies was 0.6% in May/June and the same in September/October. Even in schools with reported COVID-19 cases before the lockdown of 13 March, no clusters could be identified. Of 12 persons with positive serology five had a known history of confirmed COVID-19; 23 out of 24 participants with a household history of COVID-91 were seronegative. CONCLUSIONS: Schools do not play a crucial role in driving the SARS-CoV-2 pandemic in a low-prevalence setting. Transmission in families occurs very infrequently, and the number of unreported cases is low in this age group. These observations do not support school closures as a strategy fighting the pandemic in a low-prevalence setting. TRIAL REGISTRATION NUMBER: DRKS00022455.
  • |*COVID-19[MESH]
  • |*SARS-CoV-2[MESH]
  • |Communicable Disease Control[MESH]
  • |Germany/epidemiology[MESH]
  • |Humans[MESH]
  • |Longitudinal Studies[MESH]
  • |Schools[MESH]
  • |Seroepidemiologic Studies[MESH]


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