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10.1371/journal.pone.0251783

http://scihub22266oqcxt.onion/10.1371/journal.pone.0251783
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34111131!8191897!34111131
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suck abstract from ncbi


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pmid34111131      PLoS+One 2021 ; 16 (6): e0251783
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  • Automatic algorithm for quantifying lung involvement in patients with chronic obstructive pulmonary disease, infection with SARS-CoV-2, paracoccidioidomycosis and no lung disease patients #MMPMID34111131
  • Alves AFF; Miranda JRA; Reis F; Oliveira AA; Souza SAS; Fortaleza CMCB; Tanni SE; Castro JTS; Pina DR
  • PLoS One 2021[]; 16 (6): e0251783 PMID34111131show ga
  • In this work, we aimed to develop an automatic algorithm for the quantification of total volume and lung impairments in four different diseases. The quantification was completely automatic based upon high resolution computed tomography exams. The algorithm was capable of measuring volume and differentiating pulmonary involvement including inflammatory process and fibrosis, emphysema, and ground-glass opacities. The algorithm classifies the percentage of each pulmonary involvement when compared to the entire lung volume. Our algorithm was applied to four different patients groups: no lung disease patients, patients diagnosed with SARS-CoV-2, patients with chronic obstructive pulmonary disease, and patients with paracoccidioidomycosis. The quantification results were compared with a semi-automatic algorithm previously validated. Results confirmed that the automatic approach has a good agreement with the semi-automatic. Bland-Altman (B&A) demonstrated a low dispersion when comparing total lung volume, and also when comparing each lung impairment individually. Linear regression adjustment achieved an R value of 0.81 when comparing total lung volume between both methods. Our approach provides a reliable quantification process for physicians, thus impairments measurements contributes to support prognostic decisions in important lung diseases including the infection of SARS-CoV-2.
  • |*Algorithms[MESH]
  • |*Tomography, X-Ray Computed/methods[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19/*diagnostic imaging/physiopathology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Lung Volume Measurements/methods[MESH]
  • |Lung/*diagnostic imaging/physiopathology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Paracoccidioides/isolation & purification[MESH]
  • |Paracoccidioidomycosis/*diagnostic imaging/physiopathology[MESH]
  • |Pulmonary Disease, Chronic Obstructive/*diagnostic imaging/physiopathology[MESH]


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  • suck abstract from ncbi

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