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10.1080/08820139.2021.1936009

http://scihub22266oqcxt.onion/10.1080/08820139.2021.1936009
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suck abstract from ncbi


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pmid34109900      Immunol+Invest 2021 ; 50 (7): 802-809
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  • SARS-CoV-2: Unique Challenges of the Virus and Vaccines #MMPMID34109900
  • Mahmoodpoor A; Sanaie S; Samadi P; Yousefi M; Nader ND
  • Immunol Invest 2021[Oct]; 50 (7): 802-809 PMID34109900show ga
  • In November 2019, the highly infectious coronavirus SARS-CoV-2 emerged in Wuhan, China, and has since spread to almost all countries worldwide. Since its emergence, the COVID-19 infection has led to significant public health, economic and social problems. The current pandemic has inspired researchers to make every effort to design and develop an effective COVID-19 vaccine to provide sufficient protection against the virus and control the infection. In December 2020, the Pfizer vaccine was the first COVID-19 vaccine given Emergency Use Authorization (EUA), and the second FDA so-approved vaccine was the Moderna mRNA-1273 vaccine, which was introduced a week later. Both Pfizer and Moderna vaccines are mRNA-based vaccines, and are estimated to have an efficacy rate of more than 94%. The aim of this article is to provide a review of the attempts made to develop safe SARS-CoV-2 vaccines, highlighting potential challenges and concerns, such as disease enhancement, virus mutations, and public acceptance of the vaccine.
  • |2019-nCoV Vaccine mRNA-1273[MESH]
  • |Animals[MESH]
  • |COVID-19 Vaccines/*immunology[MESH]
  • |COVID-19/*immunology[MESH]
  • |China[MESH]
  • |Humans[MESH]


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