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10.1097/RTI.0000000000000599

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34108409!ä!34108409

suck abstract from ncbi


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pmid34108409      J+Thorac+Imaging 2021 ; 36 (5): 279-285
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  • Differences in Cardiac Magnetic Resonance Imaging Markers Between Patients With COVID-19-associated Myocardial Injury and Patients With Clinically Suspected Myocarditis #MMPMID34108409
  • Maurus S; Weckbach LT; Marschner C; Kunz WG; Ricke J; Kazmierczak PM; Bieber S; Brado J; Kraechan A; Hellmuth JC; Hausleiter J; Massberg S; Grabmaier U; Curta A
  • J Thorac Imaging 2021[Sep]; 36 (5): 279-285 PMID34108409show ga
  • PURPOSE: Coronavirus 2019 disease (COVID-19) has been shown to affect the myocardium, resulting in a worse clinical outcome. In this registry study, we aimed to identify differences in cardiac magnetic resonance imaging (CMRI) between COVID-19 and all-cause myocarditis. MATERIALS AND METHODS: We examined CMRI of patients with COVID-19 and elevated high-sensitivity serum troponin levels performed between March 31st and May 5th and compared them to CMRI of patients without SARS-CoV-2 infection with suspected myocarditis in the same time period. For this purpose, we evaluated Lake-Louise Criteria for myocarditis by determining nonischemic myocardial injury via T1-mapping, extracellular volume, late gadolinium enhancement, and myocardial edema (ME) by T2-mapping and fat-saturated T2w imaging (T2Q). RESULTS: A total of 15 of 18 (89%) patients with COVID-19 had abnormal findings. The control group consisted of 18 individuals. There were significantly fewer individuals with COVID-19 who had increased T2 (5 vs. 10; P=0.038) and all-cause ME (7 vs. 15; P=0.015); thus, significantly fewer patients with COVID-19 fulfilled Lake-Louise Criteria (6 vs. 17; P<0.001). In contrast, nonischemic myocardial injury was not significantly different. In the COVID-19 group, indexed end-diastolic volume of the left ventricle showed a significant correlation to the extent of abnormal T1 (R2=0.571; P=0.017) and extracellular volume (R2=0.605; P=0.013) and absolute T1, T2, and T2Q (R2=0.644; P=0.005, R2=0.513; P=0.035 and R2=0.629; P=0.038, respectively); in the control group, only extracellular volume showed a weak correlation (R2=0.490; P=0.046). CONCLUSIONS: Cardiac involvement in COVID-19 seems to show less ME than all-cause myocarditis. Abnormal CMRI markers correlated to left ventricle dilation only in the COVID-19 group. Larger comparative studies are needed to verify our findings.
  • |*COVID-19/diagnostic imaging[MESH]
  • |*Magnetic Resonance Imaging, Cine[MESH]
  • |*Myocarditis/diagnostic imaging[MESH]
  • |Contrast Media[MESH]
  • |Diagnosis, Differential[MESH]
  • |Gadolinium[MESH]
  • |Humans[MESH]
  • |Myocardium[MESH]


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  • suck abstract from ncbi

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