Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1186/s40001-021-00524-8 http://scihub22266oqcxt.onion/10.1186/s40001-021-00524-8 34103090!8185313!34103090     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Eur+J+Med+Res 2021 ; 26 (1): 51 Nephropedia Template TP {{tp|p=34103090|t=2021. Characterization of SARS-CoV-2 different variants and related morbidity and mortality: a systematic review |pdf=|usr=}}{{34103090}} gab.com Text Characterization of SARS-CoV-2 different variants and related morbidity and mortality: a systematic review JO: Eur J Med Res http://www.kidney.de/pget.php?&tw=1&pmid=34103090 #FOAvip INTRODUCTION: Coronavirus Disease-2019 (SARS-CoV-2) started its devastating trajectory into a global pandemic in Wuhan, China, in December 2019. Ever since, several variants of SARS-CoV-2 have been identified. In the present review, we aimed to characterize the different variants of SARS-CoV-2 and explore the related morbidity and mortality. METHODS: A systematic review including the current evidence related to different variants of SARS-CoV-2 and the related morbidity and mortality was conducted through a systematic search utilizing the keywords in the online databases including Scopus, PubMed, Web of Science, and Science Direct; we retrieved all related papers and reports published in English from December 2019 to September 2020. RESULTS: A review of identified articles has shown three main genomic variants, including type A, type B, and type C. we also identified three clades including S, V, and G. Studies have demonstrated that the C14408T and A23403G alterations in the Nsp12 and S proteins are the most prominent alterations in the world, leading to life-threatening mutations.The spike D614G amino acid change has become the most common variant since December 2019. From missense mutations found from Gujarat SARS-CoV-2 genomes, C28854T, deleterious mutation in the nucleocapsid (N) gene was significantly associated with patients' mortality. The other significant deleterious variant (G25563T) is found in patients located in Orf3a and has a potential role in viral pathogenesis. CONCLUSION: Overall, researchers identified several SARS-CoV-2 variants changing clinical manifestations and increasing the transmissibility, morbidity, and mortality of COVID-19. This should be considered in current practice and interventions to combat the pandemic and prevent related morbidity and mortality. Twit Text FOAVip Characterization of SARS-CoV-2 different variants and related morbidity and mortality: a systematic review ????Eur J Med Res http://www.kidney.de/pget.php?&tw=1&pmid=34103090 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34103090 #FOAvip English Wikipedia <ref>{{Cite pmid|34103090}}</ref> Characterization of SARS-CoV-2 different variants and related morbidity and mortality: a systematic review #MMPMID34103090 SeyedAlinaghi S; Mirzapour P; Dadras O; Pashaei Z; Karimi A; MohsseniPour M; Soleymanzadeh M; Barzegary A; Afsahi AM; Vahedi F; Shamsabadi A; Behnezhad F; Saeidi S; Mehraeen E; Shayesteh Jahanfar Eur J Med Res 2021[Jun]; 26 (1): 51 PMID34103090show ga INTRODUCTION: Coronavirus Disease-2019 (SARS-CoV-2) started its devastating trajectory into a global pandemic in Wuhan, China, in December 2019. Ever since, several variants of SARS-CoV-2 have been identified. In the present review, we aimed to characterize the different variants of SARS-CoV-2 and explore the related morbidity and mortality. METHODS: A systematic review including the current evidence related to different variants of SARS-CoV-2 and the related morbidity and mortality was conducted through a systematic search utilizing the keywords in the online databases including Scopus, PubMed, Web of Science, and Science Direct; we retrieved all related papers and reports published in English from December 2019 to September 2020. RESULTS: A review of identified articles has shown three main genomic variants, including type A, type B, and type C. we also identified three clades including S, V, and G. Studies have demonstrated that the C14408T and A23403G alterations in the Nsp12 and S proteins are the most prominent alterations in the world, leading to life-threatening mutations.The spike D614G amino acid change has become the most common variant since December 2019. From missense mutations found from Gujarat SARS-CoV-2 genomes, C28854T, deleterious mutation in the nucleocapsid (N) gene was significantly associated with patients' mortality. The other significant deleterious variant (G25563T) is found in patients located in Orf3a and has a potential role in viral pathogenesis. CONCLUSION: Overall, researchers identified several SARS-CoV-2 variants changing clinical manifestations and increasing the transmissibility, morbidity, and mortality of COVID-19. This should be considered in current practice and interventions to combat the pandemic and prevent related morbidity and mortality. |*Mutation[MESH] |COVID-19/*epidemiology/mortality/virology[MESH] |Coronavirus RNA-Dependent RNA Polymerase/*genetics[MESH] |Humans[MESH] |Morbidity[MESH] |Pandemics[MESH] |SARS-CoV-2/*genetics/pathogenicity[MESH] |Spike Glycoprotein, Coronavirus/*genetics[MESH] |Survival Rate[MESH]Characterization of SARS-CoV-2 different variants and related morbidit(epmc).pdf DeepDyve Pubget Overpricing