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Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 United+European+Gastroenterol+J 2021 ; 9 (7): 787-796 Nephropedia Template TP
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What gastroenterologists should know about SARS-CoV 2 vaccine: World Endoscopy Organization perspective #MMPMID34102015
Spadaccini M; Canziani L; Aghemo A; Lleo A; Maselli R; Anderloni A; Carrara S; Fugazza A; Pellegatta G; Galtieri PA; Hassan C; Greenwald D; Pochapin M; Wallace M; Sharma P; Roesch T; Bhandari P; Emura F; Raju GS; Repici A
United European Gastroenterol J 2021[Sep]; 9 (7): 787-796 PMID34102015show ga
BACKGROUND: The novel Coronavirus (SARS-CoV-2) has caused almost 2 million deaths worldwide. Both Food and Drug Administration and European Medicines Agency have recently approved the first COVID-19 vaccines, and a few more are going to be approved soon. METHODS: Several different approaches have been used to stimulate the immune system in mounting a humoral response. As more traditional approaches are under investigation (inactivated virus vaccines, protein subunit vaccines, recombinant virus vaccines), more recent and innovative strategies have been tried (non-replicating viral vector vaccines, RNA based vaccines, DNA based vaccines). RESULTS: Since vaccinations campaigns started in December 2020 in both the US and Europe, gastroenterologists will be one of the main sources of information regarding SARS-CoV 2 vaccination for patients in their practice, including vulnerable patients such as those with Inflammatory Bowel Disease (IBD), patients with chronic liver disease, and GI cancer patients. CONCLUSIONS: Thus, we must ourselves be well educated and updated in order to provide unambiguous counseling to these categories of vulnerable patients. In this commentary, we aim to provide a comprehensive review of both approved COVID-19 vaccines and the ones still under development, and explore potential risks, benefits and prioritization of vaccination.