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10.1007/s00705-021-05132-9

http://scihub22266oqcxt.onion/10.1007/s00705-021-05132-9
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34101005!8185311!34101005
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suck abstract from ncbi


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pmid34101005      Arch+Virol 2021 ; 166 (8): 2299-2303
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  • Antibody response in COVID-19 patients with and without re-positive RT-PCR results during the convalescent phase #MMPMID34101005
  • Peng J; Liu ZY; Yu XJ; Chen XY; Zhang K; Liu Y; Su YY; Sun CQ
  • Arch Virol 2021[Aug]; 166 (8): 2299-2303 PMID34101005show ga
  • Nucleic acid testing and antibody testing data from 143 recovered COVID-19 patients during the convalescent phase were retrospectively analyzed. A total of 23 (16.1%) recovered patients re-tested positive for SARS-CoV-2 RNA by RT-PCR. Three months after symptom onset, 100% and 99.3% of the patients remained positive for total and IgG antibodies, and the antibody levels remained high. IgM antibodies declined rapidly, with a median time to seroconversion of 67 (95% CI: 59, 75) days after onset. Approximately 25% of patients were seronegative for IgA antibodies at three months after onset. There was no statistically significant difference in antibody kinetics between patients with and without re-positive RT-PCR results during the convalescent phase.
  • |*Convalescence[MESH]
  • |Adult[MESH]
  • |Antibodies, Viral/*blood[MESH]
  • |COVID-19 Testing[MESH]
  • |COVID-19/diagnosis/*immunology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Immunoglobulin A/blood[MESH]
  • |Immunoglobulin G/blood[MESH]
  • |Immunoglobulin M/blood[MESH]
  • |Kinetics[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |RNA, Viral/genetics[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2/genetics/*immunology/isolation & purification[MESH]


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