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10.23812/THEO_EDIT_3_21 http://scihub22266oqcxt.onion/10.23812/THEO_EDIT_3_21 34100279!ä!34100279 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Biol+Regul+Homeost+Agents 2021 ; 35 (3): 833-838 Nephropedia Template TP {{tp|p=34100279|t=2021. Be aware of SARS-CoV-2 spike protein: There is more than meets the eye |pdf=|usr=}}{{34100279}} gab.com Text Be aware of SARS-CoV-2 spike protein: There is more than meets the eye JO: J Biol Regul Homeost Agents http://www.kidney.de/pget.php?&tw=1&pmid=34100279 #FOAvip The COVID-19 pandemic necessitated the rapid production of vaccines aimed at the production of neutralizing antibodies against the COVID-19 spike protein required for the corona virus binding to target cells. The best well-known vaccines have utilized either mRNA or an adenovirus vector to direct human cells to produce the spike protein against which the body produces mostly neutralizing antibodies. However, recent reports have raised some skepticism as to the biologic actions of the spike protein and the types of antibodies produced. One paper reported that certain antibodies in the blood of infected patients appear to change the shape of the spike protein so as to make it more likely to bind to cells, while other papers showed that the spike protein by itself (without being part of the corona virus) can damage endothelial cells and disrupt the blood-brain barrier. These findings may be even more relevant to the pathogenesis of long-COVID syndrome that may affect as many as 50% of those infected with SARS-CoV-2. In COVID-19, a response to oxidative stress is required by increasing anti-oxidant enzymes. In this regard, it is known that polyphenols are natural anti-oxidants with multiple health effects. Hence, there are even more reasons to intervene with the use of anti-oxidant compounds, such as luteolin, in addition to available vaccines and anti-inflammatory drugs to prevent the harmful actions of the spike protein. Twit Text FOAVip Be aware of SARS-CoV-2 spike protein: There is more than meets the eye ????J Biol Regul Homeost Agents http://www.kidney.de/pget.php?&tw=1&pmid=34100279 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34100279 #FOAvip English Wikipedia <ref>{{Cite pmid|34100279}}</ref> Be aware of SARS-CoV-2 spike protein: There is more than meets the eye #MMPMID34100279 Theoharides TC; Conti P J Biol Regul Homeost Agents 2021[May]; 35 (3): 833-838 PMID34100279show ga The COVID-19 pandemic necessitated the rapid production of vaccines aimed at the production of neutralizing antibodies against the COVID-19 spike protein required for the corona virus binding to target cells. The best well-known vaccines have utilized either mRNA or an adenovirus vector to direct human cells to produce the spike protein against which the body produces mostly neutralizing antibodies. However, recent reports have raised some skepticism as to the biologic actions of the spike protein and the types of antibodies produced. One paper reported that certain antibodies in the blood of infected patients appear to change the shape of the spike protein so as to make it more likely to bind to cells, while other papers showed that the spike protein by itself (without being part of the corona virus) can damage endothelial cells and disrupt the blood-brain barrier. These findings may be even more relevant to the pathogenesis of long-COVID syndrome that may affect as many as 50% of those infected with SARS-CoV-2. In COVID-19, a response to oxidative stress is required by increasing anti-oxidant enzymes. In this regard, it is known that polyphenols are natural anti-oxidants with multiple health effects. Hence, there are even more reasons to intervene with the use of anti-oxidant compounds, such as luteolin, in addition to available vaccines and anti-inflammatory drugs to prevent the harmful actions of the spike protein. |*COVID-19/complications[MESH] |*Spike Glycoprotein, Coronavirus/genetics[MESH] |Endothelial Cells[MESH] |Humans[MESH] |Pandemics[MESH] |Post-Acute COVID-19 Syndrome[MESH]Be aware of SARS-CoV-2 spike protein: There is more than meets the eye(epmc).pdf DeepDyve Pubget Overpricing