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Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Pediatr+Infect+Dis+J 2021 ; 40 (7): e259-e262 Nephropedia Template TP
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Rationale of Therapeutic Plasma Exchange as Rescue Immunomodulatory Treatment for MIS-C With Multiorgan Failure #MMPMID34097663
Pediatr Infect Dis J 2021[Jul]; 40 (7): e259-e262 PMID34097663show ga
Multisystem inflammatory syndrome in children (MIS-C) associated with SARS-CoV-2 infection is an infrequent and poorly understood illness. It can present as severe multiorgan failure in children, potentially lethal. Immunomodulation is the empiric treatment because a dysregulated immune response is the primary pathophysiologic mechanism. We present an infant with severe MIS-C, refractory to usual treatment, successfully treated with plasmapheresis.
|*Immunomodulation[MESH]
|*Plasma Exchange[MESH]
|COVID-19/*therapy[MESH]
|Child, Preschool[MESH]
|Female[MESH]
|Humans[MESH]
|Multiple Organ Failure/*immunology/*therapy[MESH]