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10.1016/j.ahjo.2021.100018 http://scihub22266oqcxt.onion/10.1016/j.ahjo.2021.100018 34095889!8168299!34095889     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+Heart+J+Plus 2021 ; 6 (ä): 100018 Nephropedia Template TP {{tp|p=34095889|t=2021. Understanding the role of left and right ventricular strain assessment in patients hospitalized with COVID-19 |pdf=|usr=}}{{34095889}} gab.com Text Understanding the role of left and right ventricular strain assessment in patients hospitalized with COVID-19 JO: Am Heart J Plus http://www.kidney.de/pget.php?&tw=1&pmid=34095889 #FOAvip BACKGROUND: Coronavirus disease 2019 (COVID-19) can cause cardiac injury resulting in abnormal right or left ventricular function (RV/LV) with worse outcomes. We hypothesized that two-dimensional (2D) speckle-tracking assessment of LV global longitudinal strain (GLS) and RV free wall strain (FWS) by transthoracic echocardiography can assist as markers for subclinical cardiac injury predicting increased mortality. METHODS: We performed 2D strain analysis via proprietary software in 48 patients hospitalized with COVID-19. Clinical information, demographics, comorbidities, and lab values were collected via retrospective chart review. The primary outcome was in-hospital mortality based on an optimized abnormal LV GLS value via ROC analysis and RV FWS. RESULTS: The optimal LV GLS cutoff to predict death was -13.8%, with a sensitivity of 85% (95% CI 55-98%) and specificity of 54% (95% CI 36-71%). Abnormal LV GLS >-13.8% was associated with a higher risk of death [unadjusted hazard ratio 5.15 (95% CI 1.13-23.45), p?=?0.034], which persisted after adjustment for clinical variables. Among patients with LV ejection fraction (LVEF) >50%, those with LV GLS?>?-13.8% had higher mortality compared to those with LV GLS <-13.8% (41% vs. 10%, p?=?0.030). RV FWS value was higher in patients with LV GLS >-13.8% (-13.7?+/-?5.9 vs. -19.6?+/-?6.7, p?=?0.003), but not associated with decreased survival. CONCLUSION: Abnormal LV strain with a cutoff of >-13.8% in patients with COVID-19 is associated with significantly higher risk of death. Despite normal LVEF, abnormal LV GLS predicted worse outcomes in patients hospitalized with COVID-19. There was no mortality difference based on RV strain. Twit Text FOAVip Understanding the role of left and right ventricular strain assessment in patients hospitalized with COVID-19 ????Am Heart J Plus http://www.kidney.de/pget.php?&tw=1&pmid=34095889 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34095889 #FOAvip English Wikipedia <ref>{{Cite pmid|34095889}}</ref> Understanding the role of left and right ventricular strain assessment in patients hospitalized with COVID-19 #MMPMID34095889 Park J; Kim Y; Pereira J; Hennessey KC; Faridi KF; McNamara RL; Velazquez EJ; Hur DJ; Sugeng L; Agarwal V Am Heart J Plus 2021[Jun]; 6 (ä): 100018 PMID34095889show ga BACKGROUND: Coronavirus disease 2019 (COVID-19) can cause cardiac injury resulting in abnormal right or left ventricular function (RV/LV) with worse outcomes. We hypothesized that two-dimensional (2D) speckle-tracking assessment of LV global longitudinal strain (GLS) and RV free wall strain (FWS) by transthoracic echocardiography can assist as markers for subclinical cardiac injury predicting increased mortality. METHODS: We performed 2D strain analysis via proprietary software in 48 patients hospitalized with COVID-19. Clinical information, demographics, comorbidities, and lab values were collected via retrospective chart review. The primary outcome was in-hospital mortality based on an optimized abnormal LV GLS value via ROC analysis and RV FWS. RESULTS: The optimal LV GLS cutoff to predict death was -13.8%, with a sensitivity of 85% (95% CI 55-98%) and specificity of 54% (95% CI 36-71%). Abnormal LV GLS >-13.8% was associated with a higher risk of death [unadjusted hazard ratio 5.15 (95% CI 1.13-23.45), p?=?0.034], which persisted after adjustment for clinical variables. Among patients with LV ejection fraction (LVEF) >50%, those with LV GLS?>?-13.8% had higher mortality compared to those with LV GLS <-13.8% (41% vs. 10%, p?=?0.030). RV FWS value was higher in patients with LV GLS >-13.8% (-13.7?+/-?5.9 vs. -19.6?+/-?6.7, p?=?0.003), but not associated with decreased survival. CONCLUSION: Abnormal LV strain with a cutoff of >-13.8% in patients with COVID-19 is associated with significantly higher risk of death. Despite normal LVEF, abnormal LV GLS predicted worse outcomes in patients hospitalized with COVID-19. There was no mortality difference based on RV strain. äUnderstanding the role of left and right ventricular strain assessment(epmc).pdf DeepDyve Pubget Overpricing