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Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Biocontrol+Sci 2021 ; 26 (2): 119-125 Nephropedia Template TP
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Effect of the Photocatalyst under Visible Light Irradiation in SARS-CoV-2 Stability on an Abiotic Surface #MMPMID34092715
Uema M; Yonemitsu K; Momose Y; Ishii Y; Tateda K; Inoue T; Asakura H
Biocontrol Sci 2021[]; 26 (2): 119-125 PMID34092715show ga
There is a worldwide attempt to develop prevention strategies against SARS-CoV-2 transmission. Here we examined the effectiveness of tungsten trioxide (WO(3))-based visible light-responsive photocatalyst on the inactivation of SARS-CoV-2 under different temperatures and exposure durations. The viral titer on the photocatalyst-coated glass slides decreased from 5.93 +/- 0.38 logTCID(50) /mL to 3.05 +/-. 25 logTCID(50)/mL after exposure to 3,000 lux of the visible light irradiation for 6h at 20?. On the other hand, lighting without the photocatalyst, or the photocatalyst-coat without lighting retained viral stability. Immunoblotting and electron microscopic analyses showed the reduced amounts of spike protein on the viral surface after the photocatalyst treatment. Our data suggest a possible implication of the photocatalyst on the decontamination of SARS-CoV-2 in indoor environments, thereby preventing indirect viral spread.