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10.1016/j.ctarc.2021.100406 http://scihub22266oqcxt.onion/10.1016/j.ctarc.2021.100406 34090218!8146274!34090218     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cancer+Treat+Res+Commun 2021 ; 28 (ä): 100406 Nephropedia Template TP {{tp|p=34090218|t=2021. COVID-19 patients sera induce epithelial mesenchymal transition in cancer cells |pdf=|usr=}}{{34090218}} gab.com Text COVID-19 patients sera induce epithelial mesenchymal transition in cancer cells JO: Cancer Treat Res Commun http://www.kidney.de/pget.php?&tw=1&pmid=34090218 #FOAvip Covid-19 Pneumonia of SARS-CoV-2 pandemic infection, persists to have high disease burden especially in cancer patients. Increased inflammation and thromboembolic processes are blamed to influence cancer patients more than the others but due to lack of knowledge regarding the pathophysiology of the both the virus itself and the response of the host, more basic and translational disease modeling research is needed to understand Cancer-Covid-19 interaction. In this study, serum samples from the patients, who were hospitalized due to Covid-19 pneumonia, applied to different cancer cells and cytotoxicity, motility, proliferation and gene expression analysis were performed. Serum samples derived from healthy volunteers and the fetal bovine serum that is used regularly in cell culture experiments used as controls. Hospitalized Covid-19 patients who had also cancer, were retrospectively screened, and their clinical course were recorded. Overall 12 Patient (PS) and 4 healthy serums (CS) were included in the experiments. PS applied cells showed increased motility in A549 cells as well as lost cell to cell connection in MCF7 and HCT116 cells, and induced expression of VIM, ZEB1 and SNAIL2 mRNA levels. Eight cancer diagnosed patients who were hospitalized due to Covid-19 between April and September 2020 were also reviewed retrospectively, which 5 of them were dead during SARS-CoV-2 infection. Thorax CT images of the 2 patients showed increased metastatic nodules in the lungs as of January 2021. The results of the study indicate that metastasis may be one of the prolonged consequences of COVID-19 pandemic in cancer sufferers. Twit Text FOAVip COVID-19 patients sera induce epithelial mesenchymal transition in cancer cells ????Cancer Treat Res Commun http://www.kidney.de/pget.php?&tw=1&pmid=34090218 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34090218 #FOAvip English Wikipedia <ref>{{Cite pmid|34090218}}</ref> COVID-19 patients sera induce epithelial mesenchymal transition in cancer cells #MMPMID34090218 Saygideger Y; Sezan A; Candevir A; Saygideger Demir B; Guzel E; Baydar O; Derinoz E; Komur S; Kuscu F; Ozyilmaz E; Kuleci S; Hanta I; Akkiz H; Tasova Y Cancer Treat Res Commun 2021[]; 28 (ä): 100406 PMID34090218show ga Covid-19 Pneumonia of SARS-CoV-2 pandemic infection, persists to have high disease burden especially in cancer patients. Increased inflammation and thromboembolic processes are blamed to influence cancer patients more than the others but due to lack of knowledge regarding the pathophysiology of the both the virus itself and the response of the host, more basic and translational disease modeling research is needed to understand Cancer-Covid-19 interaction. In this study, serum samples from the patients, who were hospitalized due to Covid-19 pneumonia, applied to different cancer cells and cytotoxicity, motility, proliferation and gene expression analysis were performed. Serum samples derived from healthy volunteers and the fetal bovine serum that is used regularly in cell culture experiments used as controls. Hospitalized Covid-19 patients who had also cancer, were retrospectively screened, and their clinical course were recorded. Overall 12 Patient (PS) and 4 healthy serums (CS) were included in the experiments. PS applied cells showed increased motility in A549 cells as well as lost cell to cell connection in MCF7 and HCT116 cells, and induced expression of VIM, ZEB1 and SNAIL2 mRNA levels. Eight cancer diagnosed patients who were hospitalized due to Covid-19 between April and September 2020 were also reviewed retrospectively, which 5 of them were dead during SARS-CoV-2 infection. Thorax CT images of the 2 patients showed increased metastatic nodules in the lungs as of January 2021. The results of the study indicate that metastasis may be one of the prolonged consequences of COVID-19 pandemic in cancer sufferers. |*Immune Sera/adverse effects/toxicity[MESH] |Adult[MESH] |Aged[MESH] |COVID-19/complications/*immunology[MESH] |Cell Line, Tumor[MESH] |Cell Movement[MESH] |Cell Proliferation[MESH] |Cytotoxicity, Immunologic[MESH] |Epithelial-Mesenchymal Transition/*physiology[MESH] |Female[MESH] |Humans[MESH] |Lung Neoplasms/secondary/virology[MESH] |Male[MESH] |Middle Aged[MESH]COVID-19 patients sera induce epithelial mesenchymal transition in ca(epmc).pdf DeepDyve Pubget Overpricing