Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.2967/jnumed.121.261915 http://scihub22266oqcxt.onion/10.2967/jnumed.121.261915 34088776!8805775!34088776     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Nucl+Med 2022 ; 63 (2): 274-279 Nephropedia Template TP {{tp|p=34088776|t=2022. Incidental Findings Suggestive of COVID-19 Pneumonia in Oncologic Patients Undergoing (18)F-FDG PET/CT Studies: Association Between Metabolic and Structural Lung Changes |pdf=|usr=}}{{34088776}} gab.com Text Incidental Findings Suggestive of COVID-19 Pneumonia in Oncologic Patients Undergoing (18)F-FDG PET/CT Studies: Association Between Metabolic and Structural Lung Changes JO: J Nucl Med http://www.kidney.de/pget.php?&tw=1&pmid=34088776 #FOAvip Although the novel coronavirus disease 2019 (COVID-19) can present as nonspecific clinical forms, subclinical cases represent an important route of transmission and a significant source of mortality, mainly in high-risk subpopulations such as cancer patients. A deeper knowledge of the metabolic shift in cells infected with severe acute respiratory syndrome coronavirus 2 could provide new insights about its pathogenic and host response and help to diagnose pulmonary involvement. We explored the potential added diagnostic value of (18)F-FDG PET/CT scans in asymptomatic cancer patients with suspected COVID-19 pneumonia by investigating the association between metabolic and structural changes in the lung parenchyma. Methods:(18)F-FDG PET/CT studies acquired between February 19 and May 29, 2020, were reviewed to identify those cancer patients with incidental findings suggestive of COVID-19 pneumonia. PET studies were interpreted through qualitative (visual) and semiquantitative (measurement of SUV(max)) analysis evaluating lung findings. Several characteristic signs of COVID-19 pneumonia on CT were described as COVID-19 Reporting and Data System (CO-RADS) categories (1-6). After comparing the SUV(max) of pulmonary infiltrates among different CO-RADS categories, we explored the best potential cutoffs for pulmonary SUV(max) against CO-RADS categories as the gold standard result to eliminate the possibility that the diagnosis of COVID-19 pneumonia exists. Results: On multimodal PET/CT imaging, CT signs classified as CO-RADS category 5 or 6 were found in 16 of 41 (39%) oncologic patients. SUV(max) was higher in patients with categories 5 and 6 than in patients with category 4 (6.17 +/- 0.82 vs. 3.78 +/- 0.50, P = 0.04) or categories 2 and 3 (3.59 +/- 0.41, P = 0.01). A specificity of 93.8% (95% CI, 71.7%-99.7%) and an accuracy of 92.9% were obtained when combining a CO-RADS score of 5 or 6 with an SUV(max) of 2.45 in pulmonary infiltrates. Conclusion: In asymptomatic cancer patients, the metabolic activity in lung infiltrates is closely associated with several combined tomographic changes characteristic of COVID-19 pneumonia. Multimodal (18)F-FDG PET/CT imaging could provide additional information during early diagnosis in selected predisposed patients during the pandemic. The prognostic implications of simultaneous radiologic and molecular findings in cancer patients and other subpopulations at high risk for COVID-19 pneumonia deserve further evaluation in prospective research. Twit Text FOAVip Incidental Findings Suggestive of COVID-19 Pneumonia in Oncologic Patients Undergoing (18)F-FDG PET/CT Studies: Association Between Metabolic and Structural Lung Changes ????J Nucl Med http://www.kidney.de/pget.php?&tw=1&pmid=34088776 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34088776 #FOAvip English Wikipedia <ref>{{Cite pmid|34088776}}</ref> Incidental Findings Suggestive of COVID-19 Pneumonia in Oncologic Patients Undergoing (18)F-FDG PET/CT Studies: Association Between Metabolic and Structural Lung Changes #MMPMID34088776 Wakfie-Corieh CG; Ferrando-Castagnetto F; Garcia AMB; Garcia-Esquinas MG; Candil AO; Rey CR; Cabrera-Martin MN; Cano AD; Delgado JLC J Nucl Med 2022[Feb]; 63 (2): 274-279 PMID34088776show ga Although the novel coronavirus disease 2019 (COVID-19) can present as nonspecific clinical forms, subclinical cases represent an important route of transmission and a significant source of mortality, mainly in high-risk subpopulations such as cancer patients. A deeper knowledge of the metabolic shift in cells infected with severe acute respiratory syndrome coronavirus 2 could provide new insights about its pathogenic and host response and help to diagnose pulmonary involvement. We explored the potential added diagnostic value of (18)F-FDG PET/CT scans in asymptomatic cancer patients with suspected COVID-19 pneumonia by investigating the association between metabolic and structural changes in the lung parenchyma. Methods:(18)F-FDG PET/CT studies acquired between February 19 and May 29, 2020, were reviewed to identify those cancer patients with incidental findings suggestive of COVID-19 pneumonia. PET studies were interpreted through qualitative (visual) and semiquantitative (measurement of SUV(max)) analysis evaluating lung findings. Several characteristic signs of COVID-19 pneumonia on CT were described as COVID-19 Reporting and Data System (CO-RADS) categories (1-6). After comparing the SUV(max) of pulmonary infiltrates among different CO-RADS categories, we explored the best potential cutoffs for pulmonary SUV(max) against CO-RADS categories as the gold standard result to eliminate the possibility that the diagnosis of COVID-19 pneumonia exists. Results: On multimodal PET/CT imaging, CT signs classified as CO-RADS category 5 or 6 were found in 16 of 41 (39%) oncologic patients. SUV(max) was higher in patients with categories 5 and 6 than in patients with category 4 (6.17 +/- 0.82 vs. 3.78 +/- 0.50, P = 0.04) or categories 2 and 3 (3.59 +/- 0.41, P = 0.01). A specificity of 93.8% (95% CI, 71.7%-99.7%) and an accuracy of 92.9% were obtained when combining a CO-RADS score of 5 or 6 with an SUV(max) of 2.45 in pulmonary infiltrates. Conclusion: In asymptomatic cancer patients, the metabolic activity in lung infiltrates is closely associated with several combined tomographic changes characteristic of COVID-19 pneumonia. Multimodal (18)F-FDG PET/CT imaging could provide additional information during early diagnosis in selected predisposed patients during the pandemic. The prognostic implications of simultaneous radiologic and molecular findings in cancer patients and other subpopulations at high risk for COVID-19 pneumonia deserve further evaluation in prospective research. |*Fluorodeoxyglucose F18[MESH] |*Radiopharmaceuticals[MESH] |*SARS-CoV-2[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |COVID-19/*diagnostic imaging[MESH] |Female[MESH] |Humans[MESH] |Lung/*diagnostic imaging/metabolism/pathology[MESH] |Male[MESH] |Middle Aged[MESH] |Neoplasms/*diagnostic imaging/metabolism/pathology[MESH]Incidental Findings Suggestive of COVID-19 Pneumonia in Oncologic Pati(epmc).pdf DeepDyve Pubget Overpricing