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10.1371/journal.pone.0252570 http://scihub22266oqcxt.onion/10.1371/journal.pone.0252570 34077483!8172066!34077483     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       PLoS+One 2021 ; 16 (6): e0252570 Nephropedia Template TP {{tp|p=34077483|t=2021. COVID-19 control strategies and intervention effects in resource limited settings: A modeling study |pdf=|usr=}}{{34077483}} gab.com Text COVID-19 control strategies and intervention effects in resource limited settings: A modeling study JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=34077483 #FOAvip INTRODUCTION: Many countries with weaker health systems are struggling to put together a coherent strategy against the COVID-19 epidemic. We explored COVID-19 control strategies that could offer the greatest benefit in resource limited settings. METHODS: Using an age-structured SEIR model, we explored the effects of COVID-19 control interventions-a lockdown, physical distancing measures, and active case finding (testing and isolation, contact tracing and quarantine)-implemented individually and in combination to control a hypothetical COVID-19 epidemic in Kathmandu (population 2.6 million), Nepal. RESULTS: A month-long lockdown will delay peak demand for hospital beds by 36 days, as compared to a base scenario of no intervention (peak demand at 108 days (IQR 97-119); a 2 month long lockdown will delay it by 74 days, without any difference in annual mortality, or healthcare demand volume. Year-long physical distancing measures will reduce peak demand to 36% (IQR 23%-46%) and annual morality to 67% (IQR 48%-77%) of base scenario. Following a month long lockdown with ongoing physical distancing measures and an active case finding intervention that detects 5% of the daily infection burden could reduce projected morality and peak demand by more than 99%. CONCLUSION: Limited resource settings are best served by a combination of early and aggressive case finding with ongoing physical distancing measures to control the COVID-19 epidemic. A lockdown may be helpful until combination interventions can be put in place but is unlikely to reduce annual mortality or healthcare demand. Twit Text FOAVip COVID-19 control strategies and intervention effects in resource limited settings: A modeling study ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=34077483 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34077483 #FOAvip English Wikipedia <ref>{{Cite pmid|34077483}}</ref> COVID-19 control strategies and intervention effects in resource limited settings: A modeling study #MMPMID34077483 Pandey KR; Subedee A; Khanal B; Koirala B PLoS One 2021[]; 16 (6): e0252570 PMID34077483show ga INTRODUCTION: Many countries with weaker health systems are struggling to put together a coherent strategy against the COVID-19 epidemic. We explored COVID-19 control strategies that could offer the greatest benefit in resource limited settings. METHODS: Using an age-structured SEIR model, we explored the effects of COVID-19 control interventions-a lockdown, physical distancing measures, and active case finding (testing and isolation, contact tracing and quarantine)-implemented individually and in combination to control a hypothetical COVID-19 epidemic in Kathmandu (population 2.6 million), Nepal. RESULTS: A month-long lockdown will delay peak demand for hospital beds by 36 days, as compared to a base scenario of no intervention (peak demand at 108 days (IQR 97-119); a 2 month long lockdown will delay it by 74 days, without any difference in annual mortality, or healthcare demand volume. Year-long physical distancing measures will reduce peak demand to 36% (IQR 23%-46%) and annual morality to 67% (IQR 48%-77%) of base scenario. Following a month long lockdown with ongoing physical distancing measures and an active case finding intervention that detects 5% of the daily infection burden could reduce projected morality and peak demand by more than 99%. CONCLUSION: Limited resource settings are best served by a combination of early and aggressive case finding with ongoing physical distancing measures to control the COVID-19 epidemic. A lockdown may be helpful until combination interventions can be put in place but is unlikely to reduce annual mortality or healthcare demand. |COVID-19/*prevention & control[MESH] |Communicable Disease Control/*methods/trends[MESH] |Contact Tracing/methods[MESH] |Epidemics/*prevention & control/statistics & numerical data[MESH] |Humans[MESH] |Models, Theoretical[MESH] |Physical Distancing[MESH] |Quarantine/methods[MESH]COVID-19 control strategies and intervention effects in resource limit(epmc).pdf DeepDyve Pubget Overpricing