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10.1080/14756366.2021.1924165 http://scihub22266oqcxt.onion/10.1080/14756366.2021.1924165 34074197!8174482!34074197     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Enzyme+Inhib+Med+Chem 2021 ; 36 (1): 1230-1235 Nephropedia Template TP {{tp|p=34074197|t=2021. Is carbonic anhydrase inhibition useful as a complementary therapy of Covid-19 infection?|pdf=|usr=}}{{34074197}} gab.com Text Is carbonic anhydrase inhibition useful as a complementary therapy of Covid-19 infection JO: J Enzyme Inhib Med Chem http://www.kidney.de/pget.php?&tw=1&pmid=34074197 #FOAvip The ongoing Covid-19 is a contagious disease, and it is characterised by different symptoms such as fever, cough, and shortness of breath. Rising concerns about Covid-19 have severely affected the healthcare system in all countries as the Covid-19 outbreak has developed at a rapid rate all around the globe. Intriguing, a clinically used drug, acetazolamide (a specific inhibitor of carbonic anhydrase, CA, EC 4.2.1.1), is used to treat high-altitude pulmonary oedema (HAPE), showing a high degree of clinical similarities with the pulmonary disease caused by Covid-19. In this context, this preliminary study aims to provide insights into some factors affecting the Covid-19 patients, such as hypoxaemia, hypoxia as well as the blood CA activity. We hypothesise that patients with Covid-19 problems could show a dysregulated acid-base status influenced by CA activity. These preliminary results suggest that the use of CA inhibitors as a pharmacological treatment for Covid-19 may be beneficial. Twit Text FOAVip Is carbonic anhydrase inhibition useful as a complementary therapy of Covid-19 infection ????J Enzyme Inhib Med Chem http://www.kidney.de/pget.php?&tw=1&pmid=34074197 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34074197 #FOAvip English Wikipedia <ref>{{Cite pmid|34074197}}</ref> Is carbonic anhydrase inhibition useful as a complementary therapy of Covid-19 infection? #MMPMID34074197 Deniz S; Uysal TK; Capasso C; Supuran CT; Ozensoy Guler O J Enzyme Inhib Med Chem 2021[Dec]; 36 (1): 1230-1235 PMID34074197show ga The ongoing Covid-19 is a contagious disease, and it is characterised by different symptoms such as fever, cough, and shortness of breath. Rising concerns about Covid-19 have severely affected the healthcare system in all countries as the Covid-19 outbreak has developed at a rapid rate all around the globe. Intriguing, a clinically used drug, acetazolamide (a specific inhibitor of carbonic anhydrase, CA, EC 4.2.1.1), is used to treat high-altitude pulmonary oedema (HAPE), showing a high degree of clinical similarities with the pulmonary disease caused by Covid-19. In this context, this preliminary study aims to provide insights into some factors affecting the Covid-19 patients, such as hypoxaemia, hypoxia as well as the blood CA activity. We hypothesise that patients with Covid-19 problems could show a dysregulated acid-base status influenced by CA activity. These preliminary results suggest that the use of CA inhibitors as a pharmacological treatment for Covid-19 may be beneficial. |*COVID-19 Drug Treatment[MESH] |Acetazolamide/*therapeutic use[MESH] |Acid-Base Equilibrium/drug effects[MESH] |Altitude Sickness/blood/drug therapy[MESH] |Anticonvulsants/therapeutic use[MESH] |Antiviral Agents/*therapeutic use[MESH] |Bicarbonates/blood[MESH] |COVID-19/blood/diagnostic imaging/virology[MESH] |Carbon Dioxide/blood[MESH] |Carbonic Anhydrase Inhibitors/*therapeutic use[MESH] |Carbonic Anhydrases/*blood[MESH] |Cough/blood/drug therapy/pathology/virology[MESH] |Drug Repositioning[MESH] |Dyspnea/blood/drug therapy/pathology/virology[MESH] |Fever/blood/drug therapy/pathology/virology[MESH] |Humans[MESH] |Hydrogen-Ion Concentration[MESH] |Hypertension, Pulmonary/blood/drug therapy[MESH] |Hypoxia/blood/drug therapy/pathology/virology[MESH] |Oximetry[MESH] |Research Design[MESH] |SARS-CoV-2/pathogenicity/physiology[MESH] |Severity of Illness Index[MESH]Is carbonic anhydrase inhibition useful as a complementary therapy of (epmc).pdf DeepDyve Pubget Overpricing