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10.3390/ijms22115672 http://scihub22266oqcxt.onion/10.3390/ijms22115672 34073529!8199351!34073529     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Mol+Sci 2021 ; 22 (11): ä Nephropedia Template TP {{tp|p=34073529|t=2021. Could Histamine H1 Receptor Antagonists Be Used for Treating COVID-19?|pdf=|usr=}}{{34073529}} gab.com Text Could Histamine H1 Receptor Antagonists Be Used for Treating COVID-19 JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=34073529 #FOAvip COVID-19 has rapidly become a pandemic worldwide, causing extensive and long-term health issues. There is an urgent need to identify therapies that limit SARS-CoV-2 infection and improve the outcome of COVID-19 patients. Unbalanced lung inflammation is a common feature in severe COVID-19 patients; therefore, reducing lung inflammation can undoubtedly benefit the clinical manifestations. Histamine H1 receptor (H1 receptor) antagonists are widely prescribed medications to treat allergic diseases, while recently it has emerged that they show significant promise as anti-SARS-CoV-2 agents. Here, we briefly summarize the novel use of H1 receptor antagonists in combating SARS-CoV-2 infection. We also describe the potential antiviral mechanisms of H1 receptor antagonists on SARS-CoV-2. Finally, the opportunities and challenges of the use of H1 receptor antagonists in managing COVID-19 are discussed. Twit Text FOAVip Could Histamine H1 Receptor Antagonists Be Used for Treating COVID-19 ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=34073529 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34073529 #FOAvip English Wikipedia <ref>{{Cite pmid|34073529}}</ref> Could Histamine H1 Receptor Antagonists Be Used for Treating COVID-19? #MMPMID34073529 Qu C; Fuhler GM; Pan Y Int J Mol Sci 2021[May]; 22 (11): ä PMID34073529show ga COVID-19 has rapidly become a pandemic worldwide, causing extensive and long-term health issues. There is an urgent need to identify therapies that limit SARS-CoV-2 infection and improve the outcome of COVID-19 patients. Unbalanced lung inflammation is a common feature in severe COVID-19 patients; therefore, reducing lung inflammation can undoubtedly benefit the clinical manifestations. Histamine H1 receptor (H1 receptor) antagonists are widely prescribed medications to treat allergic diseases, while recently it has emerged that they show significant promise as anti-SARS-CoV-2 agents. Here, we briefly summarize the novel use of H1 receptor antagonists in combating SARS-CoV-2 infection. We also describe the potential antiviral mechanisms of H1 receptor antagonists on SARS-CoV-2. Finally, the opportunities and challenges of the use of H1 receptor antagonists in managing COVID-19 are discussed. |*COVID-19 Drug Treatment[MESH] |Anti-Inflammatory Agents/*pharmacology[MESH] |Antiviral Agents/*pharmacology[MESH] |COVID-19/metabolism[MESH] |Histamine H1 Antagonists/*pharmacology[MESH] |Humans[MESH] |NF-kappa B/*metabolism[MESH] |Receptors, Histamine H1/metabolism[MESH] |SARS-CoV-2/*drug effects[MESH]Could Histamine H1 Receptor Antagonists Be Used for Treating COVID-19?(epmc).pdf DeepDyve Pubget Overpricing