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10.3390/vaccines9050524 http://scihub22266oqcxt.onion/10.3390/vaccines9050524 34069359!8158705!34069359     free     free     free       Vaccines+(Basel) 2021 ; 9 (5): ä Nephropedia Template TP {{tp|p=34069359|t=2021. Delivery Routes for COVID-19 Vaccines |pdf=|usr=}}{{34069359}} gab.com Text Delivery Routes for COVID-19 Vaccines JO: Vaccines (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=34069359 #FOAvip The novel coronavirus, SARS-CoV-2, which causes COVID-19, has resulted in a pandemic with millions of deaths. To eradicate SARS-CoV-2 and prevent further infections, many vaccine candidates have been developed. These vaccines include not only traditional subunit vaccines and attenuated or inactivated viral vaccines but also nucleic acid and viral vector vaccines. In contrast to the diversity in the platform technology, the delivery of vaccines is limited to intramuscular vaccination. Although intramuscular vaccination is safe and effective, mucosal vaccination could improve the local immune responses that block the spread of pathogens. However, a lack of understanding of mucosal immunity combined with the urgent need for a COVID-19 vaccine has resulted in only intramuscular vaccinations. In this review, we summarize the history of vaccines, current progress in COVID-19 vaccine technology, and the status of intranasal COVID-19 vaccines. Future research should determine the most effective route for vaccine delivery based on the platform and determine the mechanisms that underlie the efficacy of different delivery routes. Twit Text FOAVip Delivery Routes for COVID-19 Vaccines ????Vaccines (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=34069359 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34069359 #FOAvip English Wikipedia <ref>{{Cite pmid|34069359}}</ref> Delivery Routes for COVID-19 Vaccines #MMPMID34069359 Park JH; Lee HK Vaccines (Basel) 2021[May]; 9 (5): ä PMID34069359show ga The novel coronavirus, SARS-CoV-2, which causes COVID-19, has resulted in a pandemic with millions of deaths. To eradicate SARS-CoV-2 and prevent further infections, many vaccine candidates have been developed. These vaccines include not only traditional subunit vaccines and attenuated or inactivated viral vaccines but also nucleic acid and viral vector vaccines. In contrast to the diversity in the platform technology, the delivery of vaccines is limited to intramuscular vaccination. Although intramuscular vaccination is safe and effective, mucosal vaccination could improve the local immune responses that block the spread of pathogens. However, a lack of understanding of mucosal immunity combined with the urgent need for a COVID-19 vaccine has resulted in only intramuscular vaccinations. In this review, we summarize the history of vaccines, current progress in COVID-19 vaccine technology, and the status of intranasal COVID-19 vaccines. Future research should determine the most effective route for vaccine delivery based on the platform and determine the mechanisms that underlie the efficacy of different delivery routes. äDelivery Routes for COVID-19 Vaccines (epmc).pdf DeepDyve Pubget Overpricing