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10.3390/ijerph18094956

http://scihub22266oqcxt.onion/10.3390/ijerph18094956
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34066615!8124897!34066615
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suck abstract from ncbi


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pmid34066615      Int+J+Environ+Res+Public+Health 2021 ; 18 (9): ä
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  • Concurrent Heavy Metal Exposures and Idiopathic Dilated Cardiomyopathy: A Case-Control Study from the Katanga Mining Area of the Democratic Republic of Congo #MMPMID34066615
  • Malamba-Lez D; Tshala-Katumbay D; Bito V; Rigo JM; Kipenge Kyandabike R; Ngoy Yolola E; Katchunga P; Koba-Bora B; Ngoy-Nkulu D
  • Int J Environ Res Public Health 2021[May]; 18 (9): ä PMID34066615show ga
  • Blood and/or urine levels of 27 heavy metals were determined by ICPMS in 41 patients with dilated cardiomyopathy (DCM) and 29 presumably healthy subjects from the Katanga Copperbelt (KC), in the Democratic Republic of Congo (DRC). After adjusting for age, gender, education level, and renal function, DCM probability was almost maximal for blood concentrations above 0.75 and 150 microg/dL for arsenic and copper, respectively. Urinary concentrations above 1 for chromium, 20 for copper, 600 for zinc, 30 for selenium, 2 for cadmium, 0.2 for antimony, 0.5 for thallium, and 0.05 for uranium, all in mug/g of creatinine, were also associated with increased DCM probability. Concurrent and multiple exposures to heavy metals, well beyond permissible levels, are associated with increased probability for DCM. Study findings warrant screening for metal toxicity in case of DCM and prompt public health measures to reduce exposures in the KC, DRC.
  • |*Arsenic[MESH]
  • |*Cardiomyopathy, Dilated/chemically induced/epidemiology[MESH]
  • |*Metals, Heavy[MESH]
  • |Case-Control Studies[MESH]
  • |Democratic Republic of the Congo/epidemiology[MESH]
  • |Environmental Exposure/analysis[MESH]
  • |Humans[MESH]


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