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10.3390/v13050895

http://scihub22266oqcxt.onion/10.3390/v13050895
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34066046!8150338!34066046
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suck abstract from ncbi


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pmid34066046      Viruses 2021 ; 13 (5): ä
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  • Performance of Self-Collected Saliva Testing Compared with Nasopharyngeal Swab Testing for the Detection of SARS-CoV-2 #MMPMID34066046
  • Carrouel F; Valette M; Perrier H; Bouscambert-Duchamp M; Dussart C; Tramini P; Bourgeois D
  • Viruses 2021[May]; 13 (5): ä PMID34066046show ga
  • The aim of this study was to determine whether self-collected pure saliva (SCPS) is comparable to nasopharyngeal (NP) swabs in the quantitative detection of SARS-CoV-2 by RT-PCR in asymptomatic, mild patients with confirmed COVID-19. Thirty-one patients aged from 18 to 85 years were included between 9 June and 11 December 2020. A SCPS sample and a NP sample were taken for each patient. Quantitative PCR was performed to detect SARS-CoV-2 viral load. Results of SCPS vs. NP samples testing were compared. Statistical analyses were performed. Viral load was significantly correlated (r = 0.72). The concordance probability was estimated at 73.3%. In symptomatic adults, SCPS performance was similar to that of NP swabs (Percent Agreement = 74.1%; p = 0.11). Thus, the salivary test based on pure oral saliva samples easily obtained by noninvasive techniques has a fair agreement with the nasopharyngeal one in asymptomatic, mild patients with a confirmed diagnosis of COVID-19.
  • |Adult[MESH]
  • |Aged[MESH]
  • |Asymptomatic Diseases[MESH]
  • |COVID-19 Testing/*methods[MESH]
  • |COVID-19/*diagnosis[MESH]
  • |Diagnostic Tests, Routine[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Nasopharynx/*virology[MESH]
  • |RNA, Viral[MESH]
  • |Real-Time Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2/*isolation & purification[MESH]
  • |Saliva/*virology[MESH]
  • |Specimen Handling/methods[MESH]
  • |Viral Load/methods[MESH]


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