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10.3390/vaccines9050453

http://scihub22266oqcxt.onion/10.3390/vaccines9050453
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34063733!8147846!34063733
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suck abstract from ncbi


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pmid34063733      Vaccines+(Basel) 2021 ; 9 (5): ä
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  • Environmental Risk Assessment of Recombinant Viral Vector Vaccines against SARS-Cov-2 #MMPMID34063733
  • Baldo A; Leunda A; Willemarck N; Pauwels K
  • Vaccines (Basel) 2021[May]; 9 (5): ä PMID34063733show ga
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the coronavirus disease 2019 (COVID-19) pandemic. Over the past months, considerable efforts have been put into developing effective and safe drugs and vaccines against SARS-CoV-2. Various platforms are being used for the development of COVID-19 vaccine candidates: recombinant viral vectors, protein-based vaccines, nucleic acid-based vaccines, and inactivated/attenuated virus. Recombinant viral vector vaccine candidates represent a significant part of those vaccine candidates in clinical development, with two already authorised for use in the European Union and one currently under rolling review by the European Medicines Agency (EMA). Since recombinant viral vector vaccine candidates are considered as genetically modified organisms (GMOs), their regulatory oversight includes besides an assessment of their quality, safety and efficacy, also an environmental risk assessment (ERA). The present article highlights the main characteristics of recombinant viral vector vaccine (candidates) against SARS-CoV-2 in the pipeline and discusses their features from an environmental risk point of view.
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