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10.3346/jkms.2021.36.e157

http://scihub22266oqcxt.onion/10.3346/jkms.2021.36.e157
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34060263!8167408!34060263
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suck abstract from ncbi


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pmid34060263      J+Korean+Med+Sci 2021 ; 36 (21): e157
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  • Antibody Responses One Year after Mild SARS-CoV-2 Infection #MMPMID34060263
  • Choe PG; Kim KH; Kang CK; Suh HJ; Kang E; Lee SY; Kim NJ; Yi J; Park WB; Oh MD
  • J Korean Med Sci 2021[May]; 36 (21): e157 PMID34060263show ga
  • Understanding the long-term kinetics of antibodies in coronavirus disease 2019 (COVID-19) is essential in interpreting serosurvey data. We investigated the antibody response one year after infection in 52 mildly symptomatic patients with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection, using three commercial immunoassays and a surrogate virus neutralization test (sVNT) kit. Anti-N pan-immunoglobulin (Ig), anti-S IgG, and anti-S1 IgG were detected in 43 (82.7%), 44 (84.6%), and 30 (57.7%), respectively. In 49 (94.2%), the antibody could be detected by either anti-N pan-Ig or anti-S IgG assay. In the sVNT, 30 (57.7%) had positive neutralizing activity. Despite waning immunity, SARS-CoV-2 antibodies can be detected up to one year after infection, even in mild COVID-19 patients.
  • |Adult[MESH]
  • |Antibodies, Viral/*blood[MESH]
  • |COVID-19/*immunology[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Neutralization Tests[MESH]
  • |Reagent Kits, Diagnostic[MESH]
  • |SARS-CoV-2/*immunology[MESH]
  • |Time Factors[MESH]


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