Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Diagn+Microbiol+Infect+Dis 2021 ; 100 (4): 115403 Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Assay dependence of long-term kinetics of SARS-CoV-2 antibodies #MMPMID34058541
Schallier A; De Baets S; De Bruyne D; Dauwe K; Herpol M; Couck P
Diagn Microbiol Infect Dis 2021[Aug]; 100 (4): 115403 PMID34058541show ga
Since the worldwide outbreak of the novel coronavirus (SARS-CoV-2), the question raised whether infected patients would elicit long-lasting protective immunity. Several companies developed serological assays for the detection of SARS-CoV-2 antibodies. In this study, we compared 4 different serology assays in convalescents up to 7 months post-infection. Both Abbott assays showed a significative decrease of IgG antibodies over time. Whereas the Elecsys Anti?SARS?CoV?2 N assay (Roche) initially showed a significant increase, antibody titers significantly decreased at the latest timepoint. Although not significant, the Elecsys Anti?SARS?CoV?2 S assay (Roche) showed tendency towards increasing titers overtime. Our data showed that results of SARS-CoV-2 serology should be interpreted with caution.