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10.1016/j.diagmicrobio.2021.115403

http://scihub22266oqcxt.onion/10.1016/j.diagmicrobio.2021.115403
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34058541!8061083!34058541
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suck abstract from ncbi


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pmid34058541      Diagn+Microbiol+Infect+Dis 2021 ; 100 (4): 115403
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  • Assay dependence of long-term kinetics of SARS-CoV-2 antibodies #MMPMID34058541
  • Schallier A; De Baets S; De Bruyne D; Dauwe K; Herpol M; Couck P
  • Diagn Microbiol Infect Dis 2021[Aug]; 100 (4): 115403 PMID34058541show ga
  • Since the worldwide outbreak of the novel coronavirus (SARS-CoV-2), the question raised whether infected patients would elicit long-lasting protective immunity. Several companies developed serological assays for the detection of SARS-CoV-2 antibodies. In this study, we compared 4 different serology assays in convalescents up to 7 months post-infection. Both Abbott assays showed a significative decrease of IgG antibodies over time. Whereas the Elecsys Anti?SARS?CoV?2 N assay (Roche) initially showed a significant increase, antibody titers significantly decreased at the latest timepoint. Although not significant, the Elecsys Anti?SARS?CoV?2 S assay (Roche) showed tendency towards increasing titers overtime. Our data showed that results of SARS-CoV-2 serology should be interpreted with caution.
  • |Antibodies, Viral/*blood/metabolism[MESH]
  • |COVID-19 Serological Testing/*methods[MESH]
  • |COVID-19/*blood/immunology[MESH]
  • |Humans[MESH]
  • |Immunoglobulin G/*blood/metabolism[MESH]
  • |SARS-CoV-2/*immunology[MESH]
  • |Sensitivity and Specificity[MESH]


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