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10.1080/08923973.2021.1931302 http://scihub22266oqcxt.onion/10.1080/08923973.2021.1931302 34057871!8171013!34057871     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Immunopharmacol+Immunotoxicol 2021 ; 43 (4): 395-409 Nephropedia Template TP {{tp|p=34057871|t=2021. Promising drug repurposing approach targeted for cytokine storm implicated in SARS-CoV-2 complications |pdf=|usr=}}{{34057871}} gab.com Text Promising drug repurposing approach targeted for cytokine storm implicated in SARS-CoV-2 complications JO: Immunopharmacol Immunotoxicol http://www.kidney.de/pget.php?&tw=1&pmid=34057871 #FOAvip A global threat has emerged in 2019 due to the rapid spread of Coronavirus disease (COVID-19). As of January 2021, the number of cases worldwide reached 103 million cases and 2.22 million deaths which were confirmed as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This global pandemic galvanized the scientific community to study the causative virus (SARS-CoV2) pathogenesis, transmission, and clinical symptoms. Remarkably, the most common complication associated with this disease is the cytokine storm which is responsible for COVID-19 mortality. Thus, targeting the cytokine storm with new medications is needed to hamper COVID-19 complications where the most prominent strategy for the treatment is drug repurposing. Through this strategy, several steps are skipped especially those required for testing drug safety and thus may help in reducing the dissemination of this pandemic. Accordingly, the aim of this review is to outline the pathogenesis, clinical features, and immune complications of SARS-CoV2 in addition to suggesting several repurposed drugs with their plausible mechanism of action for possible management of severe COVID-19 cases. Twit Text FOAVip Promising drug repurposing approach targeted for cytokine storm implicated in SARS-CoV-2 complications ????Immunopharmacol Immunotoxicol http://www.kidney.de/pget.php?&tw=1&pmid=34057871 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34057871 #FOAvip English Wikipedia <ref>{{Cite pmid|34057871}}</ref> Promising drug repurposing approach targeted for cytokine storm implicated in SARS-CoV-2 complications #MMPMID34057871 Shawki MA; Elsayed NS; Mantawy EM; Said RS Immunopharmacol Immunotoxicol 2021[Aug]; 43 (4): 395-409 PMID34057871show ga A global threat has emerged in 2019 due to the rapid spread of Coronavirus disease (COVID-19). As of January 2021, the number of cases worldwide reached 103 million cases and 2.22 million deaths which were confirmed as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This global pandemic galvanized the scientific community to study the causative virus (SARS-CoV2) pathogenesis, transmission, and clinical symptoms. Remarkably, the most common complication associated with this disease is the cytokine storm which is responsible for COVID-19 mortality. Thus, targeting the cytokine storm with new medications is needed to hamper COVID-19 complications where the most prominent strategy for the treatment is drug repurposing. Through this strategy, several steps are skipped especially those required for testing drug safety and thus may help in reducing the dissemination of this pandemic. Accordingly, the aim of this review is to outline the pathogenesis, clinical features, and immune complications of SARS-CoV2 in addition to suggesting several repurposed drugs with their plausible mechanism of action for possible management of severe COVID-19 cases. |*COVID-19 Drug Treatment[MESH] |*Drug Repositioning[MESH] |Animals[MESH] |Anti-Inflammatory Agents/adverse effects/*therapeutic use[MESH] |COVID-19/immunology/virology[MESH] |Cytokine Release Syndrome/*drug therapy/immunology/virology[MESH] |Cytokines/*antagonists & inhibitors/immunology[MESH] |Host-Pathogen Interactions[MESH] |Humans[MESH]Promising drug repurposing approach targeted for cytokine storm implic(epmc).pdf DeepDyve Pubget Overpricing