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10.1080/17476348.2021.1937132 http://scihub22266oqcxt.onion/10.1080/17476348.2021.1937132 34056983!ä!34056983 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Expert+Rev+Respir+Med 2021 ; 15 (10): 1303-1316 Nephropedia Template TP {{tp|p=34056983|t=2021. Novel therapeutic approaches targeting endotypes of severe airway disease |pdf=|usr=}}{{34056983}} gab.com Text Novel therapeutic approaches targeting endotypes of severe airway disease JO: Expert Rev Respir Med http://www.kidney.de/pget.php?&tw=1&pmid=34056983 #FOAvip Introduction: Severe asthma and chronic rhinosinusitis (CRS), with nasal polyps (CRSwNP) and without nasal polyps (CRSsNP), are heterogeneous diseases characterized by different mechanistic pathways (endotypes) and variable clinical presentations (phenotypes).Areas covered: This review provides the clinician with an overview of the prevalence and clinical impact of severe chronic upper and lower airways disease and suggests a novel therapeutic approach with biological agents with possible biomarkers. To select relevant literature for inclusion in this review, we conducted a literature search using the PubMed database, using terms 'severe airways disease' AND 'endotype' AND 'treatment.' The literature review was performed for publication years 2010-2020, restricting the articles to humans and English language publications.Expert opinion: The coronavirus disease (COVID-19) pandemic has brought forth many challenges for patients with severe airway disease and healthcare practitioners involved in care. These patients could have an increased risk of developing severe SARS-CoV-2 disease, although treatment with biologics is not associated with a worse prognosis. Eosinopenia on hospital admission plays a key role as a diagnostic and prognostic biomarker. Twit Text FOAVip Novel therapeutic approaches targeting endotypes of severe airway disease ????Expert Rev Respir Med http://www.kidney.de/pget.php?&tw=1&pmid=34056983 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34056983 #FOAvip English Wikipedia <ref>{{Cite pmid|34056983}}</ref> Novel therapeutic approaches targeting endotypes of severe airway disease #MMPMID34056983 De Filippo M; Votto M; Licari A; Pagella F; Benazzo M; Ciprandi G; Marseglia GL Expert Rev Respir Med 2021[Oct]; 15 (10): 1303-1316 PMID34056983show ga Introduction: Severe asthma and chronic rhinosinusitis (CRS), with nasal polyps (CRSwNP) and without nasal polyps (CRSsNP), are heterogeneous diseases characterized by different mechanistic pathways (endotypes) and variable clinical presentations (phenotypes).Areas covered: This review provides the clinician with an overview of the prevalence and clinical impact of severe chronic upper and lower airways disease and suggests a novel therapeutic approach with biological agents with possible biomarkers. To select relevant literature for inclusion in this review, we conducted a literature search using the PubMed database, using terms 'severe airways disease' AND 'endotype' AND 'treatment.' The literature review was performed for publication years 2010-2020, restricting the articles to humans and English language publications.Expert opinion: The coronavirus disease (COVID-19) pandemic has brought forth many challenges for patients with severe airway disease and healthcare practitioners involved in care. These patients could have an increased risk of developing severe SARS-CoV-2 disease, although treatment with biologics is not associated with a worse prognosis. Eosinopenia on hospital admission plays a key role as a diagnostic and prognostic biomarker. |*COVID-19[MESH] |*Nasal Polyps[MESH] |*Rhinitis[MESH] |*Sinusitis[MESH] |Chronic Disease[MESH] |Humans[MESH]Novel therapeutic approaches targeting endotypes of severe airway dise(epmc).pdf DeepDyve Pubget Overpricing