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suck abstract from ncbi


10.1155/2021/5531220

http://scihub22266oqcxt.onion/10.1155/2021/5531220
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34056008!8130907!34056008
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suck abstract from ncbi

pmid34056008      J+Immunol+Res 2021 ; 2021 (?): 5531220
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  • Induction of Humoral and Cellular Immunity by Intradermal Delivery of SARS-CoV-2 Nucleocapsid Protein Using Dissolvable Microneedles #MMPMID34056008
  • Kuwentrai C; Yu J; Zhang BZ; Hu YF; Dou Y; Gong HR; Huang JD; Xu C
  • J Immunol Res 2021[]; 2021 (?): 5531220 PMID34056008show ga
  • The nucleocapsid protein (NP) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contains immunogenic epitopes that can induce cytotoxic T lymphocyte (CTL) against viral infection. This makes the nucleocapsid protein a suitable candidate for developing a vaccine against SARS-CoV-2 infection. This article reports the intradermal delivery of NP antigen using dissolvable microneedle skin patches that could induce both significant B cell and T cell responses.
  • |Animals[MESH]
  • |Antibodies, Viral/*blood[MESH]
  • |B-Lymphocytes/immunology[MESH]
  • |COVID-19 Vaccines/administration & dosage/*immunology[MESH]
  • |COVID-19/*prevention & control[MESH]
  • |Coronavirus Nucleocapsid Proteins/administration & dosage/*immunology[MESH]
  • |Enzyme-Linked Immunosorbent Assay[MESH]
  • |Injections, Intradermal/methods[MESH]
  • |Mice[MESH]
  • |Mice, Inbred BALB C[MESH]
  • |Phosphoproteins/administration & dosage/immunology[MESH]
  • |SARS-CoV-2/*immunology[MESH]


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