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10.1007/s11239-021-02487-3

http://scihub22266oqcxt.onion/10.1007/s11239-021-02487-3
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34050883!8164077!34050883
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suck abstract from ncbi


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pmid34050883      J+Thromb+Thrombolysis 2022 ; 53 (2): 321-334
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  • Impact of COVID-19 outbreak on patients with ST-segment elevation myocardial infarction (STEMI) in Turkey: results from TURSER study (TURKISH St-segment elevation myocardial infarction registry) #MMPMID34050883
  • Kiris T; Avci E; Ekin T; Akgun DE; Tiryaki M; Yidirim A; Hazir K; Murat B; Yeni M; Altindag R; Gul S; Arik B; Guzel T; Murat S; Oz A; Karabacak M; Aktas Z; Yildirim T; Kilicaslan B; Ergene AO
  • J Thromb Thrombolysis 2022[Feb]; 53 (2): 321-334 PMID34050883show ga
  • OBJECTIVE: We aimed to investigate both the impact of COVID-19 pandemic on ST-segment elevation myocardial infarction (STEMI) admission, and demographic, angiographic, procedural characteristics, and in-hospital clinical outcomes of patients with COVID-19 positive STEMI in Turkey. METHODS: This was a multi-center and cross-sectional observational study. The study population included 1788 STEMI patients from 15 centers in Turkey. The patients were divided into two groups: COVID-19 era (March 11st-May 15st, 2020; n = 733) or pre- COVID-19 era group (March 11st-May 15st, 2019; n = 1055). Also, the patients in COVID-19 era were grouped as COVID-19 positive (n = 65) or negative (n = 668). RESULTS: There was a 30.5% drop in STEMI admission during COVID-19 era in comparison to pre-COVID-19 era. The patients admitted to the medical centers during COVID-19 era had a longer symptom-to-first medical contact time [120 (75-240) vs. 100 (60-180) minutes, p < 0.001]. COVID-19 positive STEMI patients had higher thrombus grade and lower left ventricular ejection fraction compared to COVID-19 negative patients. COVID-19 positive patients had higher mortality (28% vs. 6%, p < 0.001) and cardiogenic shock (20% vs. 7%, p < 0.001) rates compared with those without COVID-19. Matching based on propensity scores showed higher mortality and high thrombus grade in STEMI patients who were infected by SARS-COV-2 (each p < 0.05). CONCLUSIONS: We detected significantly lower STEMI hospitalization rates and significant delay in duration of symptom onset to first medical contact in the context of Turkey during the COVID-19 outbreak. Moreover, high thrombus grade and mortality were more common in COVID-19 positive STEMI patients.
  • |*COVID-19/epidemiology[MESH]
  • |*ST Elevation Myocardial Infarction/diagnosis/mortality[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Hospitalization/statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Registries[MESH]
  • |SARS-CoV-2[MESH]
  • |Stroke Volume[MESH]
  • |Time-to-Treatment[MESH]
  • |Turkey/epidemiology[MESH]


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