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10.1093/ijnp/pyab024

http://scihub22266oqcxt.onion/10.1093/ijnp/pyab024
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34048557!8195092!34048557
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suck abstract from ncbi


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pmid34048557      Int+J+Neuropsychopharmacol 2021 ; 24 (9): 703-709
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  • Obsessive Compulsive Disorder During Coronavirus Disease 2019 (COVID-19): 2- and 6-Month Follow-Ups in a Clinical Trial #MMPMID34048557
  • Carmi L; Ben-Arush O; Fostick L; Cohen H; Zohar J
  • Int J Neuropsychopharmacol 2021[Sep]; 24 (9): 703-709 PMID34048557show ga
  • BACKGROUND: Psychiatric patients are perceived to be especially vulnerable during a pandemic, as it increases stress and uncertainty. Several current publications have considered obsessive-compulsive disorder (OCD) patients to be particularly vulnerable during the coronavirus disease 2019 (COVID-19), and clinicians were advised to adjust treatments accordingly. The purpose of this study was to evaluate the 2- and 6-month impacts of COVID-19 on the symptom severity of OCD patients. METHODS: A cohort of OCD patients actively treated with Exposure and Response Prevention (ERP) combined with pharmacological treatment was evaluated as part of their regular psychiatric assessment twice: 113 patients were evaluated at their 2-month follow-up and 90 patients (from that cohort) were evaluated at their 6-month follow up. RESULTS: Obsessive-compulsive symptom deterioration was not present in 84% of the patients at the 2-month follow-up and 96% of the patients at the 6-month follow-up. The results were also replicated in the OCD subgroup that included patients with contamination (washers) and illness obsessions, who were believed to be particularly vulnerable considering their obsessional content. CONCLUSIONS: OCD patients (including those with obsessions related to contamination and health) who were under active ERP and pharmacological treatment did not experience exacerbated symptoms during COVID-19 at their 2- and 6-month follow-ups.
  • |*COVID-19[MESH]
  • |*Outcome Assessment, Health Care[MESH]
  • |*Symptom Flare Up[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Cognitive Behavioral Therapy[MESH]
  • |Dopamine D2 Receptor Antagonists/therapeutic use[MESH]
  • |Female[MESH]
  • |Follow-Up Studies[MESH]
  • |Humans[MESH]
  • |Implosive Therapy[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Obsessive-Compulsive Disorder/drug therapy/*physiopathology/*therapy[MESH]
  • |Selective Serotonin Reuptake Inhibitors/therapeutic use[MESH]


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