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10.1093/ehjqcco/qcab040

http://scihub22266oqcxt.onion/10.1093/ehjqcco/qcab040
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34043762!8244536!34043762
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suck abstract from ncbi


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pmid34043762      Eur+Heart+J+Qual+Care+Clin+Outcomes 2021 ; 7 (4): 378-387
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  • Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic #MMPMID34043762
  • Shoaib A; Van Spall HGC; Wu J; Cleland JGF; McDonagh TA; Rashid M; Mohamed MO; Ahmed FZ; Deanfield J; de Belder M; Gale CP; Mamas MA
  • Eur Heart J Qual Care Clin Outcomes 2021[Jul]; 7 (4): 378-387 PMID34043762show ga
  • AIMS: We hypothesized that a decline in admissions with heart failure during COVID-19 pandemic would lead to a reciprocal rise in mortality for patients with heart failure in the community. METHODS AND RESULTS: We used National Heart Failure Audit data to identify 36 974 adults who had a hospital admission with a primary diagnosis of heart failure between February and May in either 2018, 2019, or 2020. Hospital admissions for heart failure in 2018/19 averaged 160/day but were much lower in 2020, reaching a nadir of 64/day on 27 March 2020 [incidence rate ratio (IRR): 0.40, 95% confidence interval (CI): 0.38-0.42]. The proportion discharged on guideline-recommended pharmacotherapies was similar in 2018/19 compared to the same period in 2020. Between 1 February-2020 and 31 May 2020, there was a 29% decrease in hospital deaths related to heart failure (IRR: 0.71, 95% CI: 0.67-0.75; estimated decline of 448 deaths), a 31% increase in heart failure deaths at home (IRR: 1.31, 95% CI: 1.24-1.39; estimated excess 539), and a 28% increase in heart failure deaths in care homes and hospices (IRR: 1.28, 95% CI: 1.18-1.40; estimated excess 189). All-cause, inpatient death was similar in the COVID-19 and pre-COVID-19 periods [odds ratio (OR): 1.02, 95% CI: 0.94-1.10]. After hospital discharge, 30-day mortality was higher in 2020 compared to 2018/19 (OR: 1.57, 95% CI: 1.38-1.78). CONCLUSION: Compared with the rolling daily average in 2018/19, there was a substantial decline in admissions for heart failure but an increase in deaths from heart failure in the community. Despite similar rates of prescription of guideline-recommended therapy, mortality 30 days from discharge was higher during the COVID-19 pandemic period.
  • |*COVID-19/epidemiology/prevention & control[MESH]
  • |*Communicable Disease Control/methods/organization & administration[MESH]
  • |*Heart Failure/mortality/therapy[MESH]
  • |Aged, 80 and over[MESH]
  • |Cause of Death[MESH]
  • |Clinical Audit/statistics & numerical data[MESH]
  • |Electronic Health Records/statistics & numerical data[MESH]
  • |Female[MESH]
  • |Hospital Mortality/*trends[MESH]
  • |Hospitalization/*statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Mortality[MESH]
  • |Quality of Health Care[MESH]
  • |SARS-CoV-2[MESH]
  • |Severity of Illness Index[MESH]
  • |State Medicine/standards/statistics & numerical data[MESH]


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