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10.5863/1551-6776-26.4.318

http://scihub22266oqcxt.onion/10.5863/1551-6776-26.4.318
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34035676!8139565!34035676
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suck abstract from ncbi


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pmid34035676      J+Pediatr+Pharmacol+Ther 2021 ; 26 (4): 318-338
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  • The Trilogy of SARS-CoV-2 in Pediatrics (Part 2): Multisystem Inflammatory Syndrome in Children #MMPMID34035676
  • Tran VL; Parsons S; Nuibe A
  • J Pediatr Pharmacol Ther 2021[]; 26 (4): 318-338 PMID34035676show ga
  • Multisystem Inflammatory Syndrome in Children (MIS-C) was first recognized as a novel illness in 2020 with manifestations similar to other hyperinflammatory syndromes, such as Kawasaki disease or macrophage activation syndrome. Severity varies from a self-limited febrile illness to shock requiring inotropes and mechanical ventilation. Gastrointestinal symptoms and persistent fevers are the most common clinical symptoms, with the addition of cardiac manifestations inclusive of ventricular dysfunction and coronary artery aneurysms. With no controlled trials or comparative effectiveness studies evaluating treatment of MIS-C to date, current treatment with immunomodulatory agents has mainly been derived from previous experience treating Kawasaki disease. This article provides a comprehensive review summarizing published data for the evaluation and management of MIS-C, with a focus on pharmacotherapy treatment considerations.
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