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10.1007/s15010-021-01629-2

http://scihub22266oqcxt.onion/10.1007/s15010-021-01629-2
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34032997!8145183!34032997
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suck abstract from ncbi


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pmid34032997      Infection 2021 ; 49 (5): 983-988
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  • SARS-CoV-2: big seroprevalence data from Pakistan-is herd immunity at hand? #MMPMID34032997
  • Haq M; Rehman A; Ahmad J; Zafar U; Ahmed S; Khan MA; Naveed A; Rajab H; Muhammad F; Naushad W; Aman M; Rehman HU; Ahmad S; Anwar S; Haq NU
  • Infection 2021[Oct]; 49 (5): 983-988 PMID34032997show ga
  • PURPOSE: Seroprevalence surveys from different countries have reported SARS CoV-2 antibodies below 20% even in the most adversely affected areas and herd immunity cannot be predicted till more than half of the population gets the disease. The purpose of this survey was to estimate the magnitude of community-based spread of the infection, associated immunity, and the future prospects and proximity to a 'herd community'. METHODS: The study was undertaken as a cluster randomized, cross-sectional countrywide survey. This largest community-based seroprevalence data of SARS-CoV-2 were collected between 15th and 31st July, 2020 from seven randomly selected cities belonging to the three most populous provinces of Pakistan. The FDA approved kit of ROCHE was used for detection of SARS-CoV-2 antibodies. RESULTS: Serum samples of 15,390 participants were tested for SARS CoV-2 antibodies with an overall seroprevalence of 42.4%. The seroprevalence ranged from 31.1% to 48.1% in different cities with the highest in Punjab province (44.5%). In univariable analysis, the odds of seropositivity was higher in men compared to women (OR: 1.10, 95% CI: 1.01-1.19, P < 0.05). In multivariable analysis, the risk of being seropositive was lower (OR 0.72, 95% CI: 0.60-0.87, P < 0.01) in younger group (
  • |*COVID-19[MESH]
  • |*SARS-CoV-2[MESH]
  • |Aged[MESH]
  • |Antibodies, Viral[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Immunity, Herd[MESH]
  • |Male[MESH]
  • |Pakistan/epidemiology[MESH]


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