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10.1097/YIC.0000000000000364

http://scihub22266oqcxt.onion/10.1097/YIC.0000000000000364
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34030164!8162045!34030164
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suck abstract from ncbi


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pmid34030164      Int+Clin+Psychopharmacol 2021 ; 36 (4): 221-223
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  • Doxazosin improved COVID-19 associated nightmare in a patient with major depressive disorder: a case report with a positive rechallenge #MMPMID34030164
  • Hori H
  • Int Clin Psychopharmacol 2021[Jul]; 36 (4): 221-223 PMID34030164show ga
  • This article reports on the treatment of a patient with nightmares who was treated with doxazosin of an alpha 1-adrenergic antagonists. A 71-year-old Japanese major depressive disorder (MDD) woman experienced nightmares after the coronavirus disease 2019 pandemic. She had nightmares about being chased by a coronavirus and catching the corona virus. After adding doxazosin 1 mg daily in the morning, her nightmares led to remission without side effects. We also had a rechallenge regimen with doxazosin. The nightmares ceased on the second night of the rechallenge and did not return with continued treatment. This case report suggests that doxazosin may be a useful therapeutic option to target nightmares in individuals with MDD.
  • |Adrenergic alpha-1 Receptor Antagonists/*therapeutic use[MESH]
  • |Aged[MESH]
  • |COVID-19/*psychology[MESH]
  • |Depressive Disorder, Major/*drug therapy[MESH]
  • |Doxazosin/*therapeutic use[MESH]
  • |Dreams/*drug effects[MESH]
  • |Female[MESH]
  • |Humans[MESH]


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