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10.1111/jcmm.16585 http://scihub22266oqcxt.onion/10.1111/jcmm.16585 34028178!8242448!34028178     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Cell+Mol+Med 2021 ; 25 (13): 5842-56 Nephropedia Template TP {{tp|p=34028178|t=2021. Targeting the glycans: A paradigm for host-targeted and COVID-19 drug design |pdf=|usr=}}{{34028178}} gab.com Text Targeting the glycans: A paradigm for host-targeted and COVID-19 drug design JO: J Cell Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=34028178 #FOAvip There is always a need for new approaches for the control of virus burdens caused by seasonal outbreaks, the emergence of novel viruses with pandemic potential and the development of resistance to current antiviral drugs. The outbreak of the 2019 novel coronavirus-disease COVID-19 represented a pandemic threat and declared a public health emergency of international concern. Herein, the role of glycans for the development of new drugs or vaccines, as a host-targeted approach, is discussed where may provide a front-line prophylactic or threats to protect against the current and any future respiratory-infecting virus and possibly against other respiratory pathogens. As a prototype, the role of glycans in the coronavirus infection, as well as, galectins (Gal) as the glycan-recognition agents (GRAs) in drug design are here summarized. Galectins, in particular, Gal-1 and Gal-3 are ubiquitous and important to biological systems, whose interactions with viral glycans modulate host immunity and homeostatic balance. Twit Text FOAVip Targeting the glycans: A paradigm for host-targeted and COVID-19 drug design ????J Cell Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=34028178 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34028178 #FOAvip English Wikipedia <ref>{{Cite pmid|34028178}}</ref> Targeting the glycans: A paradigm for host-targeted and COVID-19 drug design #MMPMID34028178 Pourrajab F J Cell Mol Med 2021[May]; 25 (13): 5842-56 PMID34028178show ga There is always a need for new approaches for the control of virus burdens caused by seasonal outbreaks, the emergence of novel viruses with pandemic potential and the development of resistance to current antiviral drugs. The outbreak of the 2019 novel coronavirus-disease COVID-19 represented a pandemic threat and declared a public health emergency of international concern. Herein, the role of glycans for the development of new drugs or vaccines, as a host-targeted approach, is discussed where may provide a front-line prophylactic or threats to protect against the current and any future respiratory-infecting virus and possibly against other respiratory pathogens. As a prototype, the role of glycans in the coronavirus infection, as well as, galectins (Gal) as the glycan-recognition agents (GRAs) in drug design are here summarized. Galectins, in particular, Gal-1 and Gal-3 are ubiquitous and important to biological systems, whose interactions with viral glycans modulate host immunity and homeostatic balance. äTargeting the glycans: A paradigm for host-targeted and COVID-19 drug (epmc).pdf DeepDyve Pubget Overpricing