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10.1016/j.xcrm.2021.100286

http://scihub22266oqcxt.onion/10.1016/j.xcrm.2021.100286
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suck abstract from ncbi


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pmid34027499      Cell+Rep+Med 2021 ; 2 (5): 100286
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  • SARS-CoV-2 variants: Subversion of antibody response and predicted impact on T cell recognition #MMPMID34027499
  • Altmann DM; Reynolds CJ; Boyton RJ
  • Cell Rep Med 2021[May]; 2 (5): 100286 PMID34027499show ga
  • COVID-19 variants of concern, including B.1.1.7, B.1.351, and P.1, encompass mutations facilitating immune evasion. Neutralizing antibody recognition and function may be variably impaired. We considered the impact of mutations on T cell responses. Mutations could be neutral or result in either loss or gain of predicted epitopes depending on HLA type.
  • |Antibodies, Neutralizing/*blood/immunology[MESH]
  • |Antibody Formation[MESH]
  • |COVID-19/pathology/virology[MESH]
  • |Epitopes, T-Lymphocyte/immunology[MESH]
  • |HLA Antigens/genetics[MESH]
  • |Humans[MESH]
  • |SARS-CoV-2/*immunology/isolation & purification[MESH]
  • |Spike Glycoprotein, Coronavirus/chemistry/immunology/metabolism[MESH]


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