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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Cell+Rep+Med 2021 ; 2 (5): 100286 Nephropedia Template TP
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SARS-CoV-2 variants: Subversion of antibody response and predicted impact on T cell recognition #MMPMID34027499
Altmann DM; Reynolds CJ; Boyton RJ
Cell Rep Med 2021[May]; 2 (5): 100286 PMID34027499show ga
COVID-19 variants of concern, including B.1.1.7, B.1.351, and P.1, encompass mutations facilitating immune evasion. Neutralizing antibody recognition and function may be variably impaired. We considered the impact of mutations on T cell responses. Mutations could be neutral or result in either loss or gain of predicted epitopes depending on HLA type.