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10.1177/15353702211014146 http://scihub22266oqcxt.onion/10.1177/15353702211014146 34024159!8719041!34024159     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=34024159&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Exp+Biol+Med+(Maywood) 2021 ; 246 (15): 1721-1726 Nephropedia Template TP {{tp|p=34024159|t=2021. SARS-CoV-2 variants: A double-edged sword?|pdf=|usr=}}{{34024159}} gab.com Text SARS-CoV-2 variants: A double-edged sword JO: Exp Biol Med (Maywood) http://www.kidney.de/pget.php?&tw=1&pmid=34024159 #FOAvip Since the worldwide emergence of the COVID-19 outbreak, there have been international concerns about the possible viral evolution into variants with underlying mutations that may contribute to their increased transmissibility, disease severity, risk of death, and their potential escape from the immune response or may even lead to its extinction. Rigorous surveillance has revealed the variants harboring mutations in the spike protein, the main target of neutralizing antibodies generated through vaccination or herd immunity. In this review, we have highlighted major SARS-CoV-2 variants as well as other local strains along with their specific mutations, suspected changes in their characteristics, and their impact on the current pandemic and vaccine efficacy. We have also emphasized the need to develop widely protective interventions to curb further transmission of variants. Twit Text FOAVip SARS-CoV-2 variants: A double-edged sword ????Exp Biol Med (Maywood) http://www.kidney.de/pget.php?&tw=1&pmid=34024159 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34024159 #FOAvip English Wikipedia <ref>{{Cite pmid|34024159}}</ref> SARS-CoV-2 variants: A double-edged sword? #MMPMID34024159 Jogalekar MP; Veerabathini A; Gangadaran P Exp Biol Med (Maywood) 2021[Aug]; 246 (15): 1721-1726 PMID34024159show ga Since the worldwide emergence of the COVID-19 outbreak, there have been international concerns about the possible viral evolution into variants with underlying mutations that may contribute to their increased transmissibility, disease severity, risk of death, and their potential escape from the immune response or may even lead to its extinction. Rigorous surveillance has revealed the variants harboring mutations in the spike protein, the main target of neutralizing antibodies generated through vaccination or herd immunity. In this review, we have highlighted major SARS-CoV-2 variants as well as other local strains along with their specific mutations, suspected changes in their characteristics, and their impact on the current pandemic and vaccine efficacy. We have also emphasized the need to develop widely protective interventions to curb further transmission of variants. |*COVID-19/epidemiology/prevention & control[MESH] |COVID-19 Vaccines/*pharmacology[MESH] |Host-Pathogen Interactions[MESH] |Humans[MESH] |Mutation[MESH]SARS-CoV-2 variants: A double-edged sword?(epmc).pdf DeepDyve Pubget Overpricing