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10.1021/acssensors.1c00596 http://scihub22266oqcxt.onion/10.1021/acssensors.1c00596 34019385!ä!34019385 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       ACS+Sens 2021 ; 6 (6): 2378-2385 Nephropedia Template TP {{tp|p=34019385|t=2021. Sensitive Detection of SARS-CoV-2 Using a SERS-Based Aptasensor |pdf=|usr=}}{{34019385}} gab.com Text Sensitive Detection of SARS-CoV-2 Using a SERS-Based Aptasensor JO: ACS Sens http://www.kidney.de/pget.php?&tw=1&pmid=34019385 #FOAvip We developed a new surface-enhanced Raman scattering (SERS)-based aptasensor platform capable of quantifying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lysates with a high sensitivity. In this study, a spike protein deoxyribonucleic acid (DNA) aptamer was used as a receptor, and a self-grown Au nanopopcorn surface was used as a SERS detection substrate for the sensible detection of SARS-CoV-2. A quantitative analysis of the SARS-CoV-2 lysate was performed by monitoring the change in the SERS peak intensity caused by the new binding between the aptamer DNA released from the Au nanopopcorn surface and the spike protein in the SARS-CoV-2 virion. This technique enables detecting SARS-CoV-2 with a limit of detection (LoD) of less than 10 PFU/mL within 15 min. The results of this study demonstrate the possibility of a clinical application that can dramatically improve the detection limit and accuracy of the currently commercialized SARS-CoV-2 immunodiagnostic kit. Twit Text FOAVip Sensitive Detection of SARS-CoV-2 Using a SERS-Based Aptasensor ????ACS Sens http://www.kidney.de/pget.php?&tw=1&pmid=34019385 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34019385 #FOAvip English Wikipedia <ref>{{Cite pmid|34019385}}</ref> Sensitive Detection of SARS-CoV-2 Using a SERS-Based Aptasensor #MMPMID34019385 Chen H; Park SG; Choi N; Kwon HJ; Kang T; Lee MK; Choo J ACS Sens 2021[Jun]; 6 (6): 2378-2385 PMID34019385show ga We developed a new surface-enhanced Raman scattering (SERS)-based aptasensor platform capable of quantifying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lysates with a high sensitivity. In this study, a spike protein deoxyribonucleic acid (DNA) aptamer was used as a receptor, and a self-grown Au nanopopcorn surface was used as a SERS detection substrate for the sensible detection of SARS-CoV-2. A quantitative analysis of the SARS-CoV-2 lysate was performed by monitoring the change in the SERS peak intensity caused by the new binding between the aptamer DNA released from the Au nanopopcorn surface and the spike protein in the SARS-CoV-2 virion. This technique enables detecting SARS-CoV-2 with a limit of detection (LoD) of less than 10 PFU/mL within 15 min. The results of this study demonstrate the possibility of a clinical application that can dramatically improve the detection limit and accuracy of the currently commercialized SARS-CoV-2 immunodiagnostic kit. |*COVID-19[MESH] |*SARS-CoV-2[MESH] |Humans[MESH]Sensitive Detection of SARS-CoV-2 Using a SERS-Based Aptasensor (epmc).pdf DeepDyve Pubget Overpricing