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The potential for vaccination-induced herd immunity against the SARS-CoV-2 B 1 1 7 variant #MMPMID34018481
Hodgson D; Flasche S; Jit M; Kucharski AJ
Euro Surveill 2021[May]; 26 (20): ä PMID34018481show ga
We assess the feasibility of reaching the herd immunity threshold against SARS-CoV-2 through vaccination, considering vaccine effectiveness (VE), transmissibility of the virus and the level of pre-existing immunity in populations, as well as their age structure. If highly transmissible variants of concern become dominant in areas with low levels of naturally-acquired immunity and/or in populations with large proportions of < 15 year-olds, control of infection without non-pharmaceutical interventions may only be possible with a VE >/= 80%, and coverage extended to children.