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10.1080/14760584.2021.1932475

http://scihub22266oqcxt.onion/10.1080/14760584.2021.1932475
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34015243!8171015!34015243
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suck abstract from ncbi


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pmid34015243      Expert+Rev+Vaccines 2022 ; 21 (7): 877-884
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  • Potential use of convalescent plasma for SARS-CoV-2 prophylaxis and treatment in immunocompromised and vulnerable populations #MMPMID34015243
  • Focosi D; Franchini M
  • Expert Rev Vaccines 2022[Jul]; 21 (7): 877-884 PMID34015243show ga
  • INTRODUCTION: : The ongoing SARS-CoV-2 pandemic is a serious threat for the health of immunocompromised patients. Among neutralizing antibody-based therapeutics, convalescent plasma containing polyclonal anti-SARS-CoV-2 immunoglobulins has promising results in both congenital and iatrogenic immunodeficiencies in oncohematological and transplant patients. AREAS COVERED: : This article discusses case reports, case series and controlled studies detailing the efficacy of convalescent plasma in immunocompromised patients. EXPERT OPINION: : Convalescent plasma, when administered at high neutralizing antibody titers, is a safe and effective treatment for frail immunocompromised patients. Genetic monitoring of refractory patients is recommended to intercept intra-host emergence of SARS-CoV-2 variants.
  • |*COVID-19/prevention & control/therapy[MESH]
  • |*SARS-CoV-2[MESH]
  • |Antibodies, Neutralizing[MESH]
  • |Antibodies, Viral[MESH]
  • |COVID-19 Serotherapy[MESH]
  • |Humans[MESH]
  • |Immunization, Passive/methods[MESH]
  • |Immunocompromised Host[MESH]


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