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10.1093/bioinformatics/btab397

http://scihub22266oqcxt.onion/10.1093/bioinformatics/btab397
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34014278!8241415!34014278
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suck abstract from ncbi

pmid34014278      Bioinformatics 2021 ; 37 (22): 4258-4260
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  • 3DBionotes COVID-19 edition #MMPMID34014278
  • Macias JR; Sanchez-Garcia R; Conesa P; Ramirez-Aportela E; Martinez Gonzalez M; Wert-Carvajal C; Parra-Perez AM; Segura Mora J; Horrell S; Thorn A; Sorzano COS; Carazo JM
  • Bioinformatics 2021[Nov]; 37 (22): 4258-4260 PMID34014278show ga
  • SUMMARY: The web platform 3DBionotes-WS integrates multiple web services and an interactive web viewer to provide a unified environment in which biological annotations can be analyzed in their structural context. Since the COVID-19 outbreak, new structural data from many viral proteins have been provided at a very fast pace. This effort includes many cryogenic electron microscopy (cryo-EM) studies, together with more traditional ones (X-rays, NMR), using several modeling approaches and complemented with structural predictions. At the same time, a plethora of new genomics and interactomics information (including fragment screening and structure-based virtual screening efforts) have been made available from different servers. In this context, we have developed 3DBionotes-COVID-19 as an answer to: (i) the need to explore multiomics data in a unified context with a special focus on structural information and (ii) the drive to incorporate quality measurements, especially in the form of advanced validation metrics for cryo-EM. AVAILABILITY AND IMPLEMENTATION: https://3dbionotes.cnb.csic.es/ws/covid19. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
  • |*COVID-19[MESH]
  • |*Software[MESH]
  • |Genomics[MESH]


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