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10.1038/s41392-021-00621-4

http://scihub22266oqcxt.onion/10.1038/s41392-021-00621-4
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34006829!8129697!34006829
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suck abstract from ncbi


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pmid34006829      Signal+Transduct+Target+Ther 2021 ; 6 (1): 199
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  • COVID-19 vaccines: progress and understanding on quality control and evaluation #MMPMID34006829
  • Mao Q; Xu M; He Q; Li C; Meng S; Wang Y; Cui B; Liang Z; Wang J
  • Signal Transduct Target Ther 2021[May]; 6 (1): 199 PMID34006829show ga
  • The outbreak of COVID-19 has posed a huge threat to global health and economy. Countermeasures have revolutionized norms for working, socializing, learning, and travel. Importantly, vaccines have been considered as most effective tools to combat with COVID-19. As of the beginning of 2021, >200 COVID-19 vaccine candidates, covering nearly all existing technologies and platforms, are being research and development (R&D) by multiple manufacturers worldwide. This has posed a huge obstacle to the quality control and evaluation of those candidate vaccines, especially in China, where five vaccine platforms are deployed in parallel. To accelerate the R&D progress of COVID-19 vaccines, the guidances on R&D of COVID-19 vaccine have been issued by National Regulatory Authorities or organizations worldwide. The Center for Drug Evaluation and national quality control laboratory in China have played a leading role in launching the research on quality control and evaluation in collaboration with relevant laboratories involved in the vaccine R&D, which greatly supported the progression of vaccines R&D, and accelerated the approval for emergency use and conditional marketing of currently vaccine candidates. In this paper, the progress and experience gained in quality control and evaluation of COVID-19 vaccines developed in China are summarized, which might provide references for the R&D of current and next generation of COVID-19 vaccines worldwide.
  • |*COVID-19 Vaccines/chemistry/immunology/therapeutic use[MESH]
  • |*COVID-19/immunology/prevention & control[MESH]
  • |Global Health[MESH]
  • |Humans[MESH]
  • |Quality Control[MESH]


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