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10.1007/s40291-021-00535-5 http://scihub22266oqcxt.onion/10.1007/s40291-021-00535-5 34003471!8129955!34003471     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=34003471&cmd=llinks): Failed to open stream: HTTP request failed! 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A Prospective Evaluation of the Analytical Performance of GENECUBE((R)) HQ SARS-CoV-2 and GENECUBE((R)) FLU A/B |pdf=|usr=}}{{34003471}} gab.com Text A Prospective Evaluation of the Analytical Performance of GENECUBE((R)) HQ SARS-CoV-2 and GENECUBE((R)) FLU A/B JO: Mol Diagn Ther http://www.kidney.de/pget.php?&tw=1&pmid=34003471 #FOAvip BACKGROUND: Molecular tests are the mainstay of detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, their accessibility can be limited by the long examination time and inability to evaluate multiple samples at once. OBJECTIVE: This study evaluated the analytical performance of the newly developed rapid molecular assays GENECUBE((R)) HQ SARS-CoV-2 and GENECUBE((R)) FLU A/B. METHOD: This prospective study was conducted between 14 December 2020 and 9 January 2021 at a polymerase chain reaction (PCR) center. Samples were collected from the nasopharynx with flocked swabs. Molecular tests were performed with the GENECUBE((R)) system and reference reverse transcription (RT)-PCR, and the results of the two assays were compared. RESULT: Among 1065 samples, 81 (7.6%) were positive for SARS-CoV-2 on the reference RT-PCR. Three showed discordance between GENECUBE((R)) HQ SARS-CoV-2 and the reference RT-PCR; the total, positive, and negative samples of concordance for the two assays were 99.7%, 100%, and 99.7%, respectively. All discordant cases were positive with GENECUBE((R)) HQ SARS-CoV-2 and negative with the reference RT-PCR. SARS-CoV-2 was detected in all three samples using another molecular assay for SARS-CoV-2. For GENECUBE((R)) FLU A/B, the total, positive, and negative samples of concordance for the two assays were 99.5%, 100%, and 99.1%. CONCLUSION: The GENECUBE((R)) HQ SARS-CoV-2 and GENECUBE((R)) FLU A/B demonstrated sufficient analytical performance to detect SARS-CoV-2 and influenza virus A/B. Twit Text FOAVip A Prospective Evaluation of the Analytical Performance of GENECUBE((R)) HQ SARS-CoV-2 and GENECUBE((R)) FLU A/B ????Mol Diagn Ther http://www.kidney.de/pget.php?&tw=1&pmid=34003471 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34003471 #FOAvip English Wikipedia <ref>{{Cite pmid|34003471}}</ref> A Prospective Evaluation of the Analytical Performance of GENECUBE((R)) HQ SARS-CoV-2 and GENECUBE((R)) FLU A/B #MMPMID34003471 Kiyasu Y; Akashi Y; Sugiyama A; Takeuchi Y; Notake S; Naito A; Nakamura K; Ishikawa H; Suzuki H Mol Diagn Ther 2021[Jul]; 25 (4): 495-504 PMID34003471show ga BACKGROUND: Molecular tests are the mainstay of detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, their accessibility can be limited by the long examination time and inability to evaluate multiple samples at once. OBJECTIVE: This study evaluated the analytical performance of the newly developed rapid molecular assays GENECUBE((R)) HQ SARS-CoV-2 and GENECUBE((R)) FLU A/B. METHOD: This prospective study was conducted between 14 December 2020 and 9 January 2021 at a polymerase chain reaction (PCR) center. Samples were collected from the nasopharynx with flocked swabs. Molecular tests were performed with the GENECUBE((R)) system and reference reverse transcription (RT)-PCR, and the results of the two assays were compared. RESULT: Among 1065 samples, 81 (7.6%) were positive for SARS-CoV-2 on the reference RT-PCR. Three showed discordance between GENECUBE((R)) HQ SARS-CoV-2 and the reference RT-PCR; the total, positive, and negative samples of concordance for the two assays were 99.7%, 100%, and 99.7%, respectively. All discordant cases were positive with GENECUBE((R)) HQ SARS-CoV-2 and negative with the reference RT-PCR. SARS-CoV-2 was detected in all three samples using another molecular assay for SARS-CoV-2. For GENECUBE((R)) FLU A/B, the total, positive, and negative samples of concordance for the two assays were 99.5%, 100%, and 99.1%. CONCLUSION: The GENECUBE((R)) HQ SARS-CoV-2 and GENECUBE((R)) FLU A/B demonstrated sufficient analytical performance to detect SARS-CoV-2 and influenza virus A/B. |Benchmarking[MESH] |COVID-19 Nucleic Acid Testing/instrumentation/*methods[MESH] |COVID-19/*diagnosis/virology[MESH] |Humans[MESH] |Nasopharynx/virology[MESH] |Prospective Studies[MESH] |Real-Time Polymerase Chain Reaction/instrumentation/*methods[MESH] |SARS-CoV-2/*genetics/isolation & purification[MESH]A Prospective Evaluation of the Analytical Performance of GENECUBE((R)(epmc).pdf DeepDyve Pubget Overpricing