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10.26355/eurrev_202105_25846

http://scihub22266oqcxt.onion/10.26355/eurrev_202105_25846
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34002839!ä!34002839

suck abstract from ncbi


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pmid34002839      Eur+Rev+Med+Pharmacol+Sci 2021 ; 25 (9): 3623-3631
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  • Clinical application of lung ultrasound score on COVID-19 setting: a regional experience in Southern Italy #MMPMID34002839
  • Lugara M; Oliva G; Pafundi PC; Tamburrini S; Nevola R; Gjeloshi K; Ricozzi C; Imbriani S; Padula A; Aprea C; Meo L; Cozzolino D; Cuomo G; Marrone A; Romano C; Fiorini V; Coppola MG; Corvino M; Perrella A; Ponti G; Nunnari G; Ranieri R; Ruosi C; Sasso FC; Adinolfi LE; Rinaldi L
  • Eur Rev Med Pharmacol Sci 2021[May]; 25 (9): 3623-3631 PMID34002839show ga
  • OBJECTIVE: We aimed to assess the correlation between LUS Soldati proposed score and clinical presentation, course of disease and the possible need of ventilation support/intensive care. PATIENTS AND METHODS: All consecutive patients with laboratory confirmed SARS-CoV-2 infection and hospitalized in two COVID Centers were enrolled. All patients performed blood gas analysis and lung ultrasound (LUS) at admission. The LUS acquisition was based on standard sequence of 14 peculiar anatomic landmarks with a score between 0-3 based on impairment of LUS picture. Total score was computed with their sum with a total score ranging 0 to 42, according to Soldati LUS score. We evaluated the course of hospitalization until either discharge or death, the ventilatory support and the transition in intensive care if needed. RESULTS: One hundred and fifty-six patients were included in the final analysis. Most of patients presented moderate-to-severe respiratory failure (FiO2 <20%, PaO2 <60 mmHg) and consequent recommendation to invasive mechanic ventilation (CPAP/NIV/OTI). The median ultrasound thoracic score was 28 (IQR 18-36) and most of patients could be ascertained either in a score 2 (40%) or score 3 pictures (24.4%). The bivariate correlation analysis displayed statistically significant and high positive correlations between the LUS score and the following parameters: ventilation (rho=0.481, p<0.001), lactates (rho=0.464, p<0.001), dyspnea (rho=0.398, p=0.001) mortality (rho=0.410, p=0.001). Conversely, P/F (rho= -0.663, p<0.001), pH (rho = -0.363, p=0.003) and pO2 (rho = -0.400 p=0.001) displayed significant negative correlations. CONCLUSIONS: LUS score improve the workflow and provide an optimal management both in early diagnosis and prognosis of COVID-19 related lung pathology.
  • |Aged[MESH]
  • |Blood Gas Analysis/methods/trends[MESH]
  • |COVID-19/*diagnostic imaging/*epidemiology/therapy[MESH]
  • |Female[MESH]
  • |Hospitalization/*trends[MESH]
  • |Humans[MESH]
  • |Italy/epidemiology[MESH]
  • |Lung/*diagnostic imaging[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Prospective Studies[MESH]


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