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10.2174/1570159X19666210517150418 http://scihub22266oqcxt.onion/10.2174/1570159X19666210517150418 33998993!9878961!33998993     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Neuropharmacol 2022 ; 20 (4): 693-712 Nephropedia Template TP {{tp|p=33998993|t=2022. Off-label Uses of Selective Serotonin Reuptake Inhibitors (SSRIs) |pdf=|usr=}}{{33998993}} gab.com Text Off-label Uses of Selective Serotonin Reuptake Inhibitors (SSRIs) JO: Curr Neuropharmacol http://www.kidney.de/pget.php?&tw=1&pmid=33998993 #FOAvip Psychiatric drugs have primacy for off-label prescribing. Among those, selective serotonin reuptake inhibitors (SSRIs) are highly versatile and, therefore, widely prescribed. Moreover, they are commonly considered as having a better safety profile compared to other antidepressants. Thus, when it comes to off-label prescribing, SSRIs rank among the top positions. In this review, we present the state of the art of off-label applications of selective serotonin reuptake inhibitors, ranging from migraine prophylaxis to SARS-CoV-2 antiviral properties. Research on SSRIs provided significant evidence in the treatment of premature ejaculation, both with the on-label dapoxetine 30 mg and the off-label paroxetine 20 mg. However, other than a serotoninergic syndrome, serious conditions like increased bleeding rates, hyponatremia, hepatoxicity, and post-SSRIs sexual dysfunctions, are consistently more prominent when using such compounds. These insidious side effects might be frequently underestimated during common clinical practice, especially by nonpsychiatrists. Thus, some points must be addressed when using SSRIs. Among these, a psychiatric evaluation before every administration that falls outside the regulatory agencies-approved guidelines has to be considered mandatory. For these reasons, we aim with the present article to identify the risks of inappropriate uses and to advocate the need to actively boost research encouraging future clinical trials on this topic. Twit Text FOAVip Off-label Uses of Selective Serotonin Reuptake Inhibitors (SSRIs) ????Curr Neuropharmacol http://www.kidney.de/pget.php?&tw=1&pmid=33998993 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33998993 #FOAvip English Wikipedia <ref>{{Cite pmid|33998993}}</ref> Off-label Uses of Selective Serotonin Reuptake Inhibitors (SSRIs) #MMPMID33998993 Jannini TB; Lorenzo GD; Bianciardi E; Niolu C; Toscano M; Ciocca G; Jannini EA; Siracusano A Curr Neuropharmacol 2022[]; 20 (4): 693-712 PMID33998993show ga Psychiatric drugs have primacy for off-label prescribing. Among those, selective serotonin reuptake inhibitors (SSRIs) are highly versatile and, therefore, widely prescribed. Moreover, they are commonly considered as having a better safety profile compared to other antidepressants. Thus, when it comes to off-label prescribing, SSRIs rank among the top positions. In this review, we present the state of the art of off-label applications of selective serotonin reuptake inhibitors, ranging from migraine prophylaxis to SARS-CoV-2 antiviral properties. Research on SSRIs provided significant evidence in the treatment of premature ejaculation, both with the on-label dapoxetine 30 mg and the off-label paroxetine 20 mg. However, other than a serotoninergic syndrome, serious conditions like increased bleeding rates, hyponatremia, hepatoxicity, and post-SSRIs sexual dysfunctions, are consistently more prominent when using such compounds. These insidious side effects might be frequently underestimated during common clinical practice, especially by nonpsychiatrists. Thus, some points must be addressed when using SSRIs. Among these, a psychiatric evaluation before every administration that falls outside the regulatory agencies-approved guidelines has to be considered mandatory. For these reasons, we aim with the present article to identify the risks of inappropriate uses and to advocate the need to actively boost research encouraging future clinical trials on this topic. |*COVID-19 Drug Treatment[MESH] |*Selective Serotonin Reuptake Inhibitors/therapeutic use[MESH] |Ejaculation[MESH] |Humans[MESH] |Male[MESH] |Off-Label Use[MESH]Off-label Uses of Selective Serotonin Reuptake Inhibitors (SSRIs) (epmc).pdf DeepDyve Pubget Overpricing