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10.1177/03913988211016473

http://scihub22266oqcxt.onion/10.1177/03913988211016473
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33998306!ä!33998306

suck abstract from ncbi


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pmid33998306      Int+J+Artif+Organs 2021 ; 44 (12): 1034-1038
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  • Successful use of CytoSorb in a Covid-19 patient with secondary septic shock due to a sacral decubitus infection #MMPMID33998306
  • Pancani F; Pavani R; Quacquarelli A; Feri M
  • Int J Artif Organs 2021[Dec]; 44 (12): 1034-1038 PMID33998306show ga
  • Septic shock is a clinical condition with high mortality (40%-70%) and morbidity. During septic shock, there is a significant release of cytokines and other inflammatory mediators that can cause damage to different organs, known as a "cytokine storm." The cytokine storm can cause hypotension, tissue damage, metabolic acidosis, and renal failure. This clinical picture also seems to be confirmed in the context of Covid-19 patients. Hemoadsorption with CytoSorb represents an adjunctive therapy to attenuate the systemic inflammatory process and helps restore a balanced immune response. We present the clinical case of a 75-year-old man, admitted to our hospital with respiratory failure due to Sars-CoV-2 infection and secondary septic shock due to a sacral decubitus. On admission the patient presented with a clinical picture of mixed acidosis with high levels of lactate and inflammatory indexes. Simultaneously along with antibiotic therapy, we started hemoadsorption treatment with CytoSorb in combination with continuous venous-venous hemodiafiltration. At the end of the treatment the patient had recovered his vital functions and the infection was successfully treated. Use of the CytoSorb device in a Covid-19 positive patient was safe and well-tolerated. Early treatment with CytoSorb decreased interleukin 6 plasma levels and inflammatory indexes, resulting in earlier stabilization of homeostasis. This case report suggests that the use of CytoSorb could be a possible adjuvant therapy in patients with septic shock even when affected by Covid-19.
  • |*COVID-19[MESH]
  • |*Shock, Septic/therapy[MESH]
  • |Aged[MESH]
  • |Cytokines[MESH]
  • |Humans[MESH]
  • |Inflammation Mediators[MESH]
  • |Male[MESH]


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