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10.1155/2021/5571144

http://scihub22266oqcxt.onion/10.1155/2021/5571144
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33997012!8090453!33997012
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suck abstract from ncbi


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pmid33997012      Biomed+Res+Int 2021 ; 2021 (ä): 5571144
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  • Correlation between Chest X-Ray Severity in COVID-19 and Age in Mexican-Mestizo Patients: An Observational Cross-Sectional Study #MMPMID33997012
  • Albrandt-Salmeron A; Espejo-Fonseca R; Roldan-Valadez E
  • Biomed Res Int 2021[]; 2021 (ä): 5571144 PMID33997012show ga
  • INTRODUCTION: Chest X-ray (CXR) is used for the initial triage of patients with suspected COVID-19. Studies of CXR scoring in the European population found a higher score in males than in females and significantly correlated with age. Because there have not been studies in the Mexican-mestizo community, we aimed to compare the differences in CXR scores between males and females and their correlation with age after controlling comorbidities like diabetes and hypertension. MATERIALS AND METHODS: A retrospective study of 1000 CXR of Mexican-mestizo patients with SARS-CoV-2 infection, confirmed by RT-PCR. Significant differences between age, age groups, symptoms, comorbidities, and CXR scores between males and females used the Mann-Whitney U, Chi-square tests (chi (2)), and Kruskal-Wallis tests. The relationship between the total CXR score and age was measured with the Spearman rank correlation coefficient (Rs); partial correlation analysis controlled the effect of symptoms, risk factors, and comorbidities. RESULTS: The total CXR score did not show a difference between males and females grouped by age. There was a positive, low correlation between the total CXR score and age in males, Rs = 0.260, p < 0.001 (N = 616), and in females, Rs = 0.170, p = 0.001 (N = 384). Age only explained a <9% variance of CXR severity. Rs decreased its magnitude (from Rs = 0.152 to Rs = 0.046) and lost its significance (change in p value from p < 0.001 to p = 0.145) after controlling the effect of hypertension. CONCLUSIONS: There is no significant difference in CXR score between males and females in the Mexican-mestizo population grouped by age. Hypertension cancels the significance of CXR severity with age pointing to its role in the pathophysiology of COVID-19. Further research using stratified groups by age and gender in other populations needs to be published.
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/*diagnostic imaging/epidemiology/ethnology[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Lung/*diagnostic imaging[MESH]
  • |Male[MESH]
  • |Mexico/epidemiology[MESH]
  • |Middle Aged[MESH]
  • |Radiography, Thoracic[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2/isolation & purification[MESH]
  • |Severity of Illness Index[MESH]


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