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10.1016/j.lungcan.2021.05.007

http://scihub22266oqcxt.onion/10.1016/j.lungcan.2021.05.007
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33994016!8105127!33994016
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suck abstract from ncbi


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pmid33994016      Lung+Cancer 2021 ; 157 (ä): 79-84
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  • Impact of COVID-19 on the management of patients with thoracic cancers in a tertiary referral center #MMPMID33994016
  • Basse C; Daniel C; Livartowski A; Beaucaire-Danel S; Girard N
  • Lung Cancer 2021[Jul]; 157 (ä): 79-84 PMID33994016show ga
  • INTRODUCTION: Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 has spread worldwide in 2020 leading the World Health Organization to declare a pandemic. Patients with thoracic cancers have been reported at higher risk to develop severe disease, and die from COVID-19. In this setting, clinical practice recommendations for the management of patients were published. We report here how these guidelines were implemented in a routine practice setting. METHODS: We retrospectively collected the characteristics, treatment regimen and modification, as well as COVID-19 status and death for all patients with thoracic malignancies scheduled for an appointment at Institute Curie from March 23(rd) to April 17(th) 2020. RESULTS: A total of 339 patients were included. Treatment strategy was modified for a total of 110 (32 %) patients because of COVID-19; these modifications were in accordance with guidelines for 92 % of patients. The majority of dose modifications were related to immune checkpoint inhibitors, for which switch to flat dosing every 4-6 weeks was made. A total of 5 (1.5 %) patients were diagnosed with COVID-19 disease, 1 of whom died from disease complication. CONCLUSION: Our study provides a unique insight in the decision making for patients with thoracic malignancies in the setting of COVID-19 outbreak, showing how guidelines were implemented in the clinic, and what may be optimized in the clinical practice of thoracic oncology in the future.
  • |*COVID-19[MESH]
  • |*Lung Neoplasms/drug therapy/epidemiology[MESH]
  • |*Thoracic Neoplasms/epidemiology/therapy[MESH]
  • |Humans[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]


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