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10.1093/bib/bbab113 http://scihub22266oqcxt.onion/10.1093/bib/bbab113 33993214!8194848!33993214     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Brief+Bioinform 2021 ; 22 (6): ä Nephropedia Template TP {{tp|p=33993214|t=2021. Structure-based drug repurposing against COVID-19 and emerging infectious diseases: methods, resources and discoveries |pdf=|usr=}}{{33993214}} gab.com Text Structure-based drug repurposing against COVID-19 and emerging infectious diseases: methods, resources and discoveries JO: Brief Bioinform http://www.kidney.de/pget.php?&tw=1&pmid=33993214 #FOAvip To attain promising pharmacotherapies, researchers have applied drug repurposing (DR) techniques to discover the candidate medicines to combat the coronavirus disease 2019 (COVID-19) outbreak. Although many DR approaches have been introduced for treating different diseases, only structure-based DR (SBDR) methods can be employed as the first therapeutic option against the COVID-19 pandemic because they rely on the rudimentary information about the diseases such as the sequence of the severe acute respiratory syndrome coronavirus 2 genome. Hence, to try out new treatments for the disease, the first attempts have been made based on the SBDR methods which seem to be among the proper choices for discovering the potential medications against the emerging and re-emerging infectious diseases. Given the importance of SBDR approaches, in the present review, well-known SBDR methods are summarized, and their merits are investigated. Then, the databases and software applications, utilized for repurposing the drugs against COVID-19, are introduced. Besides, the identified drugs are categorized based on their targets. Finally, a comparison is made between the SBDR approaches and other DR methods, and some possible future directions are proposed. Twit Text FOAVip Structure-based drug repurposing against COVID-19 and emerging infectious diseases: methods, resources and discoveries ????Brief Bioinform http://www.kidney.de/pget.php?&tw=1&pmid=33993214 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33993214 #FOAvip English Wikipedia <ref>{{Cite pmid|33993214}}</ref> Structure-based drug repurposing against COVID-19 and emerging infectious diseases: methods, resources and discoveries #MMPMID33993214 Masoudi-Sobhanzadeh Y; Salemi A; Pourseif MM; Jafari B; Omidi Y; Masoudi-Nejad A Brief Bioinform 2021[Nov]; 22 (6): ä PMID33993214show ga To attain promising pharmacotherapies, researchers have applied drug repurposing (DR) techniques to discover the candidate medicines to combat the coronavirus disease 2019 (COVID-19) outbreak. Although many DR approaches have been introduced for treating different diseases, only structure-based DR (SBDR) methods can be employed as the first therapeutic option against the COVID-19 pandemic because they rely on the rudimentary information about the diseases such as the sequence of the severe acute respiratory syndrome coronavirus 2 genome. Hence, to try out new treatments for the disease, the first attempts have been made based on the SBDR methods which seem to be among the proper choices for discovering the potential medications against the emerging and re-emerging infectious diseases. Given the importance of SBDR approaches, in the present review, well-known SBDR methods are summarized, and their merits are investigated. Then, the databases and software applications, utilized for repurposing the drugs against COVID-19, are introduced. Besides, the identified drugs are categorized based on their targets. Finally, a comparison is made between the SBDR approaches and other DR methods, and some possible future directions are proposed. |*COVID-19 Drug Treatment[MESH] |*Drug Repositioning[MESH] |Antiviral Agents/*chemistry/therapeutic use[MESH] |COVID-19/virology[MESH] |Humans[MESH] |Pandemics[MESH]Structure-based drug repurposing against COVID-19 and emerging infecti(epmc).pdf DeepDyve Pubget Overpricing